KIM-1/TIM-1 in proximal tubular cell immune response

SRC family kinase FYN promotes the neuroendocrine phenotype and visceral metastasis in advanced prostate cancer

Mitochondrial retrograde signaling inhibits the survival during prolong S/G2 arrest in Saccharomyces cerevisiae

MKP1 mediates chemosensitizer effects of E1a in response to cisplatin in non-small cell lung carcinoma cells

Enhancement of adoptive T cell transfer with single low dose pretreatment of doxorubicin or paclitaxel in mice

Cytokine secretion and NK cell activity in human ADAM17 deficiency

Cancer stem cell targeted therapy: progress amid controversies

Foxo3a-mediated overexpression of microRNA-622 suppresses tumor metastasis by repressing hypoxia-inducible factor-1α in ERK-responsive lung cancer

Phenotype and function of CXCR5+CD45RA−CD4+ T cells were altered in HBV-related hepatocellular carcinoma and elevated serum CXCL13 predicted better prognosis

FN14 and GRP94 expression are prognostic/predictive biomarkers of brain metastasis outcome that open up new therapeutic strategies

244-MPT overcomes gefitinib resistance in non-small cell lung cancer cells

The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo

Radioresistant human lung adenocarcinoma cells that survived multiple fractions of ionizing radiation are sensitive to HSP90 inhibition

Increased expression of CX43 on stromal cells promotes leukemia apoptosis

Implication of epithelial-mesenchymal transition in IGF1R-induced resistance to EGFR-TKIs in advanced non-small cell lung cancer

Infiltrating T cells promote renal cell carcinoma (RCC) progression via altering the estrogen receptor β-DAB2IP signals

RNase L is a negative regulator of cell migration

JAM3 methylation status as a biomarker for diagnosis of preneoplastic and neoplastic lesions of the cervix

Estrogen and estrogen receptor alpha promotes malignancy and osteoblastic tumorigenesis in prostate cancer

Metabolic reprogramming: a new relevant pathway in adult adrenocortical tumors

Epigenetic silencing of tumor suppressor miR-3151 contributes to Chinese chronic lymphocytic leukemia by constitutive activation of MADD/ERK and PIK3R2/AKT signaling pathways

Anti-cancer effect of bee venom on colon cancer cell growth by activation of death receptors and inhibition of nuclear factor kappa B

Knock out CD44 in reprogrammed liver cancer cell C3A increases CSCs stemness and promotes differentiation

Upregulation of miR-181c contributes to chemoresistance in pancreatic cancer by inactivating the Hippo signaling pathway

The Janus-faced roles of Krüppel-like factor 4 in oral squamous cell carcinoma cells

Aberrantly upregulated TRAP1 is required for tumorigenesis of breast cancer

Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer

Ell3 stabilizes p53 following CDDP treatment via its effects on ubiquitin-dependent and -independent proteasomal degradation pathways in breast cancer cells

Deregulation of the miR-222-ABCG2 regulatory module in tongue squamous cell carcinoma contributes to chemoresistance and enhanced migratory/invasive potential

Connective tissue growth factor as a novel therapeutic target in high grade serous ovarian cancer

Formononetin, a novel FGFR2 inhibitor, potently inhibits angiogenesis and tumor growth in preclinical models

Suppression of tumor angiogenesis by metformin treatment via a mechanism linked to targeting of HER2/HIF-1α/VEGF secretion axis

Tamoxifen therapy benefit predictive signature coupled with prognostic signature of post-operative recurrent risk for early stage ER+ breast cancer

Tumor invasion and metastasis regulated by microRNA-184 and microRNA-574-5p in small-cell lung cancer

EpCAM based capture detects and recovers circulating tumor cells from all subtypes of breast cancer except claudin-low

PPARα induces cell apoptosis by destructing Bcl2

Effect of ceritinib (LDK378) on enhancement of chemotherapeutic agents in ABCB1 and ABCG2 overexpressing cells in vitro and in vivo

Mutant p53 induces EZH2 expression and promotes epithelial–mesenchymal transition by disrupting p68-Drosha complex assembly and attenuating miR-26a processing

Src and STAT3 inhibitors synergize to promote tumor inhibition in renal cell carcinoma

Stimulation of dendritic cells by DAMPs in ALA-PDT treated SCC tumor cells

Loss of function mutations in PTPN6 promote STAT3 deregulation via JAK3 kinase in diffuse large B-cell lymphoma

A network-based method to evaluate quality of reproducibility of differential expression in cancer genomics studies

Expression of androgen receptor splice variants in clinical breast cancers

Single-Molecule Localization Microscopy allows for the analysis of cancer metastasis-specific miRNA distribution on the nanoscale

Radiation and SN38 treatments modulate the expression of microRNAs, cytokines and chemokines in colon cancer cells in a p53-directed manner

A comparison of isolated circulating tumor cells and tissue biopsies using whole-genome sequencing in prostate cancer

Expression profiling reveals transcriptional regulation by Fbxw7/mTOR pathway in radiation-induced mouse thymic lymphomas

Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma

Tumor suppressive effect of PARP1 and FOXO3A in gastric cancers and its clinical implications

Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways

ACSL4 promotes prostate cancer growth, invasion and hormonal resistance

Differentiation between genetic mutations of breast cancer by breath volatolomics

Genomic responses to hepatitis B virus (HBV) infection in primary human hepatocytes

Sensitivity of human pleural mesothelioma to oncolytic measles virus depends on defects of the type I interferon response

mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells

TMSB4Y is a candidate tumor suppressor on the Y chromosome and is deleted in male breast cancer

The transglutaminase type 2 and pyruvate kinase isoenzyme M2 interplay in autophagy regulation

Clinical significance of age at diagnosis among young non-small cell lung cancer patients under 40 years old: a population-based study

Phase II clinical and exploratory biomarker study of dacomitinib in recurrent and/or metastatic esophageal squamous cell carcinoma

A prospective, multicenter, observational study of long-term decitabine treatment in patients with myelodysplastic syndrome

Patterns of care and treatment outcomes in older patients with biliary tract cancer