BMP9/ALK1 inhibits neovascularization in mouse models of age-related macular degeneration

Biological relevance of fatty acyl heterogeneity to the neural membrane dynamics of Rhesus macaques during normative aging

Porcine reproductive and respiratory syndrome virus triggers mitochondrial fission and mitophagy to attenuate apoptosis

Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche

Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: Involvement in the modulation of blood-brain barrier integrity

Resveratrol counteracts lipopolysaccharide-induced depressive-like behaviors via enhanced hippocampal neurogenesis

Overexpression of complement component C5a accelerates the development of atherosclerosis in ApoE-knockout mice

Butyrate alleviates high fat diet-induced obesity through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice

The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination

OASIS 2: online application for survival analysis 2 with features for the analysis of maximal lifespan and healthspan in aging research

Mechanism of BRG1 silencing in primary cancers

Memo interacts with c-Src to control Estrogen Receptor alpha sub-cellular localization

Targeting Zfp148 activates p53 and reduces tumor initiation in the gut

Overexpressed LAPTM4B-35 is a risk factor for cancer recurrence and poor prognosis in non-small-cell lung cancer

MicroRNA-564 is downregulated in glioblastoma and inhibited proliferation and invasion of glioblastoma cells by targeting TGF-β1

The lncRNA MALAT1 is a novel biomarker for gastric cancer metastasis

Novel anti-CD3 chimeric antigen receptor targeting of aggressive T cell malignancies

Expression of PD-1 on CD4⁺ T cells in peripheral blood associates with poor clinical outcome in non-small cell lung cancer

The photosensitizer verteporfin has light-independent anti-leukemic activity for Ph-positive acute lymphoblastic leukemia and synergistically works with dasatinib

Smac mimetic LCL161 overcomes protective ER stress induced by obatoclax, synergistically causing cell death in multiple myeloma

Loss of MYC and E-box3 binding contributes to defective MYC-mediated transcriptional suppression of human MC-let-7a-1~let-7d in glioblastoma

Procoagulant and immunogenic properties of melanoma exosomes, microvesicles and apoptotic vesicles

Gasdermin B expression predicts poor clinical outcome in HER2-positive breast cancer

Nuclear IKKα mediates microRNA-7/-103/107/21 inductions to downregulate maspin expression in response to HBx overexpression

Microenvironment mediated alterations to metabolic pathways confer increased chemo-resistance in CD133⁺ tumor initiating cells

EZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis

TAM receptors Tyro3 and Mer as novel targets in colorectal cancer

Combining GRP78 suppression and MK2206-induced Akt inhibition decreases doxorubicin-induced P-glycoprotein expression and mitigates chemoresistance in human osteosarcoma

Construction and analysis of dysregulated lncRNA-associated ceRNA network identified novel lncRNA biomarkers for early diagnosis of human pancreatic cancer

Intratumoral heterogeneity of the therapeutical response to gemcitabine and metformin

Inhibition of the colony-stimulating-factor-1 receptor affects the resistance of lung cancer cells to cisplatin

C-Myc functions as a competing endogenous RNA in acute promyelocytic leukemia

DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma

Significant impact of amount of PCR input templates on various PCR-based DNA methylation analysis and countermeasure

Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma

[⁶⁴Cu]XYIMSR-06: A dual-motif CAIX ligand for PET imaging of clear cell renal cell carcinoma

Identification of genetic variants predictive of early onset pancreatic cancer through a population science analysis of functional genomic datasets

Clinical benefit of a precision medicine based approach for guiding treatment of refractory cancers

Association of the GLB1 rs4678680 genetic variant with risk of HBV-related hepatocellular carcinoma

The in vitro and vivo anti-tumor effects and molecular mechanisms of suberoylanilide hydroxamic acid (SAHA) and MG132 on the aggressive phenotypes of gastric cancer cells

The prognostic value of CSCs biomarker CD133 in NSCLC: a meta-analysis

XIAP RING domain mediates miR-4295 expression and subsequently inhibiting p63α protein translation and promoting transformation of bladder epithelial cells

Pregnane X-receptor promotes stem cell-mediated colon cancer relapse

Increased frequency of circulating Th22 cells in patients with B-cell non-Hodgkin’s lymphoma

Lysosome-associated membrane glycoprotein 1 predicts fratricide amongst T cell receptor transgenic CD8⁺ T cells directed against tumor-associated antigens

Notch1 directly induced CD133 expression in human diffuse type gastric cancers

Urban-rural disparity of overweight/obesity distribution and its potential trend with breast cancer among Chinese women

Fatal gastrointestinal toxicity with ipilimumab after BRAF/ MEK inhibitor combination in a melanoma patient achieving pathological complete response

miR-199a-3p targets stemness-related and mitogenic signaling pathways to suppress the expansion and tumorigenic capabilities of prostate cancer stem cells

Decreased fucosylated PSA as a urinary marker for high Gleason score prostate cancer

Guttiferone K suppresses cell motility and metastasis of hepatocellular carcinoma by restoring aberrantly reduced profilin 1

Met promotes the formation of double minute chromosomes induced by Sei-1 in NIH-3T3 murine fibroblasts

Next generation multi-scale biophysical characterization of high precision cancer particle radiotherapy using clinical proton, helium-, carbon- and oxygen ion beams

Seven protective miRNA signatures for prognosis of cervical cancer

Regulation of cellular quiescence by YAP/TAZ and Cyclin E1 in colon cancer cells: Implication in chemoresistance and cancer relapse

Slowing down glioblastoma progression in mice by running or the anti-malarial drug dihydroartemisinin? Induction of oxidative stress in murine glioblastoma therapy

Comparative proteomic profiling of refractory/relapsed multiple myeloma reveals biomarkers involved in resistance to bortezomib-based therapy

Genetic variations in apoptosis pathway and the risk of ovarian cancer

Genomic complexity and dynamics of clonal evolution in childhood acute myeloid leukemia studied with whole-exome sequencing

An integrative framework to identify cell death-related microRNAs in esophageal squamous cell carcinoma

Delphinidin induces apoptosis via cleaved HDAC3-mediated p53 acetylation and oligomerization in prostate cancer cells

Gene expression analysis of TIL rich HPV-driven head and neck tumors reveals a distinct B-cell signature when compared to HPV independent tumors

Methylation of S100A8 is a promising diagnosis and prognostic marker in hepatocellular carcinoma

Inhibition of Mnk enhances apoptotic activity of cytarabine in acute myeloid leukemia cells

IGF-1R inhibition sensitizes breast cancer cells to ATM-related kinase (ATR) inhibitor and cisplatin

Targeting XBP1-mediated β-catenin expression associated with bladder cancer with newly synthetic Oridonin analogues

Tumor exosome-mediated promotion of adhesion to mesothelial cells in gastric cancer cells

Inhibition of cyclin dependent kinase 9 by dinaciclib suppresses cyclin B1 expression and tumor growth in triple negative breast cancer

Fulvestrant inhibits growth of triple negative breast cancer and synergizes with tamoxifen in ERα positive breast cancer by up-regulation of ERβ

Caveolin-1 promotes Ewing sarcoma metastasis regulating MMP-9 expression through MAPK/ERK pathway

A three-dimensional collagen scaffold cell culture system for screening anti-glioma therapeutics

Association between dietary nitrate and nitrite intake and site-specific cancer risk: evidence from observational studies

Loss of ARID1A expression leads to sensitivity to ROS-inducing agent elesclomol in gynecologic cancer cells

IGF-II induced by hepatitis B virus X protein regulates EMT via SUMO mediated loss of E-cadherin in mice

A role for activated Cdc42 in glioblastoma multiforme invasion

Telomere status in chronic lymphocytic leukemia with TP53 disruption

Functional intratumoral lymphatics in patient-derived xenograft models of squamous cell carcinoma of the uterine cervix: implications for lymph node metastasis

A retrospective analysis in patients with EGFR-mutant lung adenocarcinoma: is EGFR mutation associated with a higher incidence of brain metastasis?

Functional single nucleotide polymorphisms within the cyclin-dependent kinase inhibitor 2A/2B region affect pancreatic cancer risk

Targeted deep sequencing improves outcome stratification in chronic myelomonocytic leukemia with low risk cytogenetic features

Coexistence of JAK2 and CALR mutations and their clinical implications in patients with essential thrombocythemia

HPV16 E6-E7 induces cancer stem-like cells phenotypes in esophageal squamous cell carcinoma through the activation of PI3K/Akt signaling pathway in vitro and in vivo

Twist1-induced epithelial-mesenchymal transition according to microsatellite instability status in colon cancer cells

Differential expression of cyclooxygenase-2 in metastatic melanoma affects progression free survival

Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells

MiRNA-22 inhibits oncogene galectin-1 in hepatocellular carcinoma

Ablation of human telomerase reverse transcriptase (hTERT) induces cellular senescence in gastric cancer through a galectin-3 dependent mechanism

GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers

Analysis of the chemotherapeutic effects of a propadiene compound on malignant ovarian cancer cells

DR5 mAb-conjugated, DTIC-loaded immuno-nanoparticles effectively and specifically kill malignant melanoma cells in vivo

Combinatorial therapeutic targeting of BMP2 and MEK-ERK pathways in NF1-associated malignant peripheral nerve sheath tumors

O-GlcNAcylation of ATG4B positively regulates autophagy by increasing its hydroxylase activity

The VEGF rise in blood of bevacizumab patients is not based on tumor escape but a host-blockade of VEGF clearance

Celecoxib and sulindac inhibit TGF-β1-induced epithelial-mesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1

The gain and loss of long noncoding RNA associated-competing endogenous RNAs in prostate cancer

Integrative analysis of miRNA and gene expression reveals regulatory networks in tamoxifen-resistant breast cancer

miR-31 targets ARID1A and enhances the oncogenicity and stemness of head and neck squamous cell carcinoma

Optical imaging of gastric cancer with near-infrared heptamethine carbocyanine fluorescence dyes

Predictive value of chemotherapy-related high-density lipoprotein cholesterol (HDL) elevation in patients with colorectal cancer receiving adjuvant chemotherapy: an exploratory analysis of 851 cases

Fulvestrant 500 mg vs 250 mg in postmenopausal women with estrogen receptor-positive advanced breast cancer: a randomized, double-blind registrational trial in China

A phase II study of concurrent chemoradiotherapy and erlotinib for inoperable esophageal squamous cell carcinoma

Preoperative chemoradiotherapy creates an opportunity to perform sphincter preserving resection for low-lying locally advanced rectal cancer based on an oncologic outcome study

uPA/uPAR and SERPINE1 in head and neck cancer: role in tumor resistance, metastasis, prognosis and therapy

Local hyperthermia in head and neck cancer: mechanism, application and advance

LncRNAs in pancreatic cancer

Necroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapy

NETs: organ-related epigenetic derangements and potential clinical applications

Progress and perspective of TBX6 gene in congenital vertebral malformations

Potential role of the N-MYC downstream-regulated gene family in reprogramming cancer metabolism under hypoxia

Epigenetics in myeloid derived suppressor cells: a sheathed sword towards cancer

Genetic polymorphisms of mTOR and cancer risk: a systematic review and updated meta-analysis