Oncotarget

November 1, 2016

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About The Cover

The cover for issue 44 of Oncotarget features Figure 5G, "Targeting distinct phases of the angiogenic response using anti-angiogenic agents with distinct mechanisms of action," from Brennen, et al

Table of Contents

Research Perspective: Immunology

Aspergillus fumigatus responds to natural killer (NK) cells with upregulation of stress related genes and inhibits the immunoregulatory function of NK cells

Aspergillus fumigatus responds to natural killer (NK) cells with upregulation of stress related genes and inhibits the immunoregulatory function of NK cells

https://doi.org/10.18632/oncotarget.12616

Andreas Schneider, Michael Blatzer, Wilfried Posch, Ralf Schubert, Cornelia Lass-Flörl, Stanislaw Schmidt,  and Thomas Lehrnbecher
71062-71071
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Treadmill running exercise prevents senile osteoporosis and upregulates the Wnt signaling pathway in SAMP6 mice

Treadmill running exercise prevents senile osteoporosis and upregulates the Wnt signaling pathway in SAMP6 mice

https://doi.org/10.18632/oncotarget.12125

Xi Chen, Lihui Li, Jianmin Guo, Lingli Zhang, Yu Yuan, Binglin Chen, Zhongguang Sun, Jiake Xu,  and Jun Zou
71072-71086
Abstract  |  PDF  |  HTML  |  How to cite

Research Papers: Pathology

Systematically characterizing dysfunctional long intergenic non-coding RNAs in multiple brain regions of major psychosis

Systematically characterizing dysfunctional long intergenic non-coding RNAs in multiple brain regions of major psychosis

https://doi.org/10.18632/oncotarget.12122

Jing Hu, Jinyuan Xu, Lin Pang, Hongying Zhao, Feng Li, Yulan Deng, Ling Liu, Yujia Lan, Xinxin Zhang, Tingting Zhao, Chaohan Xu, Chun Xu, Yun Xiao,  and Xia Li
71087-71098
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Research Papers: Immunology

TIM-4 is expressed on invariant NKT cells but dispensable for their development and function

TIM-4 is expressed on invariant NKT cells but dispensable for their development and function

https://doi.org/10.18632/oncotarget.12153

Xilin Zhang, Jun Gu, Li Zhou,  and Qing-Sheng Mi
71099-71111
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Mesenchymal stem cells overexpressing Sirt1 inhibit prostate cancer growth by recruiting natural killer cells and macrophages

Mesenchymal stem cells overexpressing Sirt1 inhibit prostate cancer growth by recruiting natural killer cells and macrophages

https://doi.org/10.18632/oncotarget.12737

Yang Yu, Qingyun Zhang, Qinggui Meng, Chen Zong, Lei Liang, Xue Yang, Rui Lin, Yan Liu, Yang Zhou, Hongxiang Zhang, Xiaojuan Hou, Zhipeng Han,  and Jiwen Cheng
71112-71122
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Research Papers

Similarity and diversity of the tumor microenvironment in multiple metastases: critical implications for overall and progression-free survival of high-grade serous ovarian cancer

Similarity and diversity of the tumor microenvironment in multiple metastases: critical implications for overall and progression-free survival of high-grade serous ovarian cancer

https://doi.org/10.18632/oncotarget.12106

Andreas Heindl, Chunyan Lan, Daniel Nava Rodrigues, Konrad Koelble,  and Yinyin Yuan
71123-71135
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

c-Cbl mediates the degradation of tumorigenic nuclear β-catenin contributing to the heterogeneity in Wnt activity in colorectal tumors

c-Cbl mediates the degradation of tumorigenic nuclear β-catenin contributing to the heterogeneity in Wnt activity in colorectal tumors

https://doi.org/10.18632/oncotarget.12107

Moshe Shashar, Jamaica Siwak, Umit Tapan, Shin Yin Lee, Rosana D. Meyer, Paige Parrack, Josenia Tan, Fatemeh Khatami, Jean Francis, Qing Zhao, Kevan Hartshorn, Vijaya B. Kolachalama, Nader Rahimi,  and Vipul Chitalia
71136-71150
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Suppression of endogenous lipogenesis induces reversion of the malignant phenotype and normalized differentiation in breast cancer

Suppression of endogenous lipogenesis induces reversion of the malignant phenotype and normalized differentiation in breast cancer

https://doi.org/10.18632/oncotarget.9463

Anatilde M. Gonzalez-Guerrico, Ingrid Espinoza, Barbara Schroeder, Cheol Hong Park, Chandra Mohan KVP, Ashwani Khurana, Bruna Corominas-Faja, Elisabet Cuyàs, Tomás Alarcón, Celina Kleer, Javier A. Menendez,  and Ruth Lupu
71151-71168
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Low disabled-2 expression promotes tumor progression and determines poor survival and high recurrence of esophageal squamous cell carcinoma

Low disabled-2 expression promotes tumor progression and determines poor survival and high recurrence of esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.8460

Wen-Lun Wang, Wei-Lun Chang, Hsiao-Bai Yang, Yu-Chi Wang, I-Wei Chang, Ching-Tai Lee, Chi-Yang Chang, Jaw-Town Lin,  and Bor-Shyang Sheu
71169-71181
Abstract  |  PDF  |  HTML  |  How to cite

A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct

A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct

https://doi.org/10.18632/oncotarget.11511

Cory A. Ocasio, Mohan B. Rajasekaran, Sarah Walker, Darren Le Grand, John Spencer, Frances M.G. Pearl, Simon E. Ward, Velibor Savic, Laurence H. Pearl, Helfrid Hochegger,  and Antony W. Oliver
71182-71197
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Prognostic value of PDL1 expression in pancreatic cancer

Prognostic value of PDL1 expression in pancreatic cancer

https://doi.org/10.18632/oncotarget.11685

David J. Birnbaum, Pascal Finetti, Alexia Lopresti, Marine Gilabert, Flora Poizat, Olivier Turrini, Jean-Luc Raoul, Jean-Robert Delpero, Vincent Moutardier, Daniel Birnbaum, Emilie Mamessier,  and François Bertucci
71198-71210
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma

Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma

https://doi.org/10.18632/oncotarget.12078

Clemens Krepler, Min Xiao, Minu Samanta, Adina Vultur, Hsin-Yi Chen, Patricia Brafford, Patricia I. Reyes-Uribe, Molly Halloran, Thomas Chen, Xu He, Denitsa Hristova, Qin Liu, Ahmed A. Samatar, Michael A. Davies, Katherine L. Nathanson, Mizuho Fukunaga-Kalabis, Meenhard Herlyn,  and Jessie Villanueva
71211-71222
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Impact of label-free technologies in head and neck cancer circulating tumour cells

Impact of label-free technologies in head and neck cancer circulating tumour cells

https://doi.org/10.18632/oncotarget.12086

Arutha Kulasinghe, Liz Kenny, Chris Perry, Jean-Paul Thiery, Lidija Jovanovic, Ian Vela, Colleen Nelson,  and Chamindie Punyadeera
71223-71234
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Profiles of miRNAs matched to biology in aromatase inhibitor resistant breast cancer

Profiles of miRNAs matched to biology in aromatase inhibitor resistant breast cancer

https://doi.org/10.18632/oncotarget.12103

Reiner Hoppe, Ping Fan, Florian Büttner, Stefan Winter, Amit K. Tyagi, Heather Cunliffe, V. Craig Jordan,  and Hiltrud Brauch
71235-71254
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Gamma-interferon-inducible, lysosome/endosome-localized thiolreductase, GILT, has anti-retroviral activity and its expression is counteracted by HIV-1

Gamma-interferon-inducible, lysosome/endosome-localized thiolreductase, GILT, has anti-retroviral activity and its expression is counteracted by HIV-1

https://doi.org/10.18632/oncotarget.12104

Yoshinao Kubo, Mai Izumida, Yuka Yashima, Haruka Yoshii-Kamiyama, Yuetsu Tanaka, Kiyoshi Yasui, Hideki Hayashi,  and Toshifumi Matsuyama
71255-71273
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Recombinant heat shock protein 70 functional peptide and alpha-fetoprotein epitope peptide vaccine elicits specific anti-tumor immunity

Recombinant heat shock protein 70 functional peptide and alpha-fetoprotein epitope peptide vaccine elicits specific anti-tumor immunity

https://doi.org/10.18632/oncotarget.12464

Xiao-Ping Wang, Qiao-Xia Wang, Huan-Ping Lin, Bing Xu, Qian Zhao,  and Kun Chen
71274-71284
Abstract  |  PDF  |  HTML  |  How to cite

Glycodelin is a potential novel follow-up biomarker for malignant pleural mesothelioma

Glycodelin is a potential novel follow-up biomarker for malignant pleural mesothelioma

https://doi.org/10.18632/oncotarget.12474

Marc A. Schneider, Thomas Muley, Nicolas C. Kahn, Arne Warth, Michael Thomas, Felix J.F. Herth, Hendrik Dienemann,  and Michael Meister
71285-71297
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Assessing angiogenic responses induced by primary human prostate stromal cells in a three-dimensional fibrin matrix assay

Assessing angiogenic responses induced by primary human prostate stromal cells in a three-dimensional fibrin matrix assay

https://doi.org/10.18632/oncotarget.11347

W. Nathaniel Brennen, Huong Nguyen, Susan L. Dalrymple, Stephanie Reppert-Gerber, Jeesun Kim, John T. Isaacs,  and Hans Hammers
71298-71308
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-β pathway

Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-β pathway

https://doi.org/10.18632/oncotarget.11885

Loreto Boix, Juan Manuel López-Oliva, Ana Carolina Rhodes,  and Jordi Bruix
71309-71329
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Circulating tumor cell is a common property of brain glioma and promotes the monitoring system

Circulating tumor cell is a common property of brain glioma and promotes the monitoring system

https://doi.org/10.18632/oncotarget.11114

Faliang Gao, Yong Cui, Haihui Jiang, Dali Sui, Yonggang Wang, Zhongli Jiang, Jizong Zhao,  and Song Lin
71330-71340
Abstract  |  PDF  |  HTML  |  How to cite

Halofuginone inhibits radiotherapy-induced epithelial-mesenchymal transition in lung cancer

Halofuginone inhibits radiotherapy-induced epithelial-mesenchymal transition in lung cancer

https://doi.org/10.18632/oncotarget.11217

Yang Chen, Weishuai Liu, Peng Wang, Hailing Hou, Ningbo Liu, Linlin Gong, Youyou Wang, Kai Ji, Lujun Zhao,  and Ping Wang
71341-71352
Abstract  |  PDF  |  HTML  |  How to cite

Blood RNA expression profiles undergo major changes during the seventh decade

Blood RNA expression profiles undergo major changes during the seventh decade

https://doi.org/10.18632/oncotarget.12098

Marius Gheorghe, Claudia Schurmann, Marjolein J. Peters, André G. Uitterlinden, Albert Hofman, Reiner Biffar, Georg Homuth, Uwe Völker, Joyce BJ van Meurs,  and Vered Raz
71353-71361
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Dormant tumor cells expressing LOXL2 acquire a stem-like phenotype mediating their transition to proliferative growth

Dormant tumor cells expressing LOXL2 acquire a stem-like phenotype mediating their transition to proliferative growth

https://doi.org/10.18632/oncotarget.12109

Keren Weidenfeld, Sagi Schif-Zuck, Hanan Abu-Tayeh, Keunsoo Kang, Ofra Kessler, Marina Weissmann, Gera Neufeld,  and Dalit Barkan
71362-71377
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Targeting p53-deficient chronic lymphocytic leukemia cells in vitro and in vivo by ROS-mediated mechanism

Targeting p53-deficient chronic lymphocytic leukemia cells in vitro and in vivo by ROS-mediated mechanism

https://doi.org/10.18632/oncotarget.12110

Jinyun Liu, Gang Chen, Helene Pelicano, Jianwei Liao, Jie Huang, Li Feng, Michael J. Keating,  and Peng Huang
71378-71389
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

X-radiation enhances the collagen type I strap formation and migration potentials of colon cancer cells

X-radiation enhances the collagen type I strap formation and migration potentials of colon cancer cells

https://doi.org/10.18632/oncotarget.12111

Stephanie Blockhuys, Na Liu, Nisha Rani Agarwal, Annika Enejder, Vesa Loitto,  and Xiao-Feng Sun
71390-71399
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

STC2 promotes the epithelial-mesenchymal transition of colorectal cancer cells through AKT-ERK signaling pathways

STC2 promotes the epithelial-mesenchymal transition of colorectal cancer cells through AKT-ERK signaling pathways

https://doi.org/10.18632/oncotarget.12147

Bing Chen, Xiao Zeng, Yu He, Xixi Wang, Ziwei Liang, Jingjing Liu, Peng Zhang, Hongxia Zhu, Ningzhi Xu,  and Shufang Liang
71400-71416
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Acetylation of androgen receptor by ARD1 promotes dissociation from HSP90 complex and prostate tumorigenesis

Acetylation of androgen receptor by ARD1 promotes dissociation from HSP90 complex and prostate tumorigenesis

https://doi.org/10.18632/oncotarget.12163

John S. DePaolo, Zehua Wang, Jianhui Guo, Guanyi Zhang, Chiping Qian, Haitao Zhang, Jovanny Zabaleta,  and Wanguo Liu
71417-71428
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Fibroblast growth factor receptor (FGFR) alterations in squamous differentiated bladder cancer: a putative therapeutic target for a small subgroup

Fibroblast growth factor receptor (FGFR) alterations in squamous differentiated bladder cancer: a putative therapeutic target for a small subgroup

https://doi.org/10.18632/oncotarget.12198

Philipp H. Baldia, Angela Maurer, Timon Heide, Michael Rose, Robert Stoehr, Arndt Hartmann, Sarah V. Williams, Margaret A. Knowles, Ruth Knuechel,  and Nadine T. Gaisa
71429-71439
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Reproducibility with repeat CT in radiomics study for rectal cancer

Reproducibility with repeat CT in radiomics study for rectal cancer

https://doi.org/10.18632/oncotarget.12199

Panpan Hu, Jiazhou Wang, Haoyu Zhong, Zhen Zhou, Lijun Shen, Weigang Hu,  and Zhen Zhang
71440-71446
Abstract  |  PDF  |  HTML  |  How to cite

Single nucleotide polymorphisms in microRNA genes are associated with cervical cancer susceptibility in a population from Xinjiang Uygur

Single nucleotide polymorphisms in microRNA genes are associated with cervical cancer susceptibility in a population from Xinjiang Uygur

https://doi.org/10.18632/oncotarget.12212

Jie Yang, Zegao Zhang, Wen Guo, Yuhua Ma, Raila Muhammed Emin, Karima Abudubari, Glmira Hayrat, Hasiyet Wali, Xiaoli Qi, Chunhua Liu, Miaomiao Ma,  and Pulat Nurbek
71447-71454
Abstract  |  PDF  |  HTML  |  How to cite

CD8+/FOXP3+ ratio and PD-L1 expression associated with survival in pT3N0M0 stage esophageal squamous cell cancer

CD8+/FOXP3+ ratio and PD-L1 expression associated with survival in pT3N0M0 stage esophageal squamous cell cancer

https://doi.org/10.18632/oncotarget.12213

Yingming Zhu, Minghuan Li, Dianbin Mu, Li Kong, Jianbo Zhang, Fen Zhao, Zhenxiang Li, Xuemei Liu, Cong Bo,  and Jinming Yu
71455-71465
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Targeting endogenous DLK1 exerts antitumor effect on hepatocellular carcinoma through initiating cell differentiation

Targeting endogenous DLK1 exerts antitumor effect on hepatocellular carcinoma through initiating cell differentiation

https://doi.org/10.18632/oncotarget.12214

Chun-Miao Cai, Xu Xiao, Bing-Hao Wu, Bao-Feng Wei,  and Ze-Guang Han
71466-71476
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

The human nucleophosmin 1 mutation A inhibits myeloid differentiation of leukemia cells by modulating miR-10b

The human nucleophosmin 1 mutation A inhibits myeloid differentiation of leukemia cells by modulating miR-10b

https://doi.org/10.18632/oncotarget.12216

Qin Zou, Shi Tan, Zailin Yang, Juan Wang, Jingrong Xian, Shuaishuai Zhang, Hongjun Jin, Liyuan Yang, Lu Wang,  and Ling Zhang
71477-71490
Abstract  |  PDF  |  HTML  |  How to cite

Tumor-initiating cell frequency is relevant for glioblastoma aggressiveness

Tumor-initiating cell frequency is relevant for glioblastoma aggressiveness

https://doi.org/10.18632/oncotarget.11600

Cristina Richichi, Daniela Osti, Massimiliano Del Bene, Lorenzo Fornasari, Monica Patanè, Bianca Pollo, Francesco DiMeco,  and Giuliana Pelicci
71491-71503
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

MicroRNA regulatory pathway analysis identifies miR-142-5p as a negative regulator of TGF-β pathway via targeting SMAD3

MicroRNA regulatory pathway analysis identifies miR-142-5p as a negative regulator of TGF-β pathway via targeting SMAD3

https://doi.org/10.18632/oncotarget.12229

Zhaowu Ma, Teng Liu, Wei Huang, Hui Liu, Hong-Mei Zhang, Qiubai Li, Zhichao Chen,  and An-Yuan Guo
71504-71513
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Paired proteomics, transcriptomics and miRNomics in non-small cell lung cancers: known and novel signaling cascades

Paired proteomics, transcriptomics and miRNomics in non-small cell lung cancers: known and novel signaling cascades

https://doi.org/10.18632/oncotarget.11723

Christina Backes, Nicole Ludwig, Petra Leidinger, Hanno Huwer, Stefan Tenzer, Tobias Fehlmann, Andre Franke, Eckart Meese, Hans-Peter Lenhof,  and Andreas Keller
71514-71525
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Prognostic nomogram for previously untreated adult patients with acute myeloid leukemia

Prognostic nomogram for previously untreated adult patients with acute myeloid leukemia

https://doi.org/10.18632/oncotarget.12245

Zhuojun Zheng, Xiaodong Li, Yuandong Zhu, Weiying Gu, Xiaobao Xie,  and Jingting Jiang
71526-71535
Abstract  |  PDF  |  HTML  |  How to cite

A CD22-reactive TCR from the T-cell allorepertoire for the treatment of acute lymphoblastic leukemia by TCR gene transfer

A CD22-reactive TCR from the T-cell allorepertoire for the treatment of acute lymphoblastic leukemia by TCR gene transfer

https://doi.org/10.18632/oncotarget.12247

Lorenz Jahn, Renate S. Hagedoorn, Dirk M. van der Steen, Pleun Hombrink, Michel G.D. Kester, Marjolein P. Schoonakker, Daniëlle de Ridder, Peter A. van Veelen, J.H. Frederik Falkenburg,  and Mirjam H.M. Heemskerk
71536-71547
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Comparative effectiveness of image-guided radiotherapy for non-operated localized esophageal squamous cell carcinoma patients receiving concurrent chemoradiotherapy: A population-based propensity score matched analysis

Comparative effectiveness of image-guided radiotherapy for non-operated localized esophageal squamous cell carcinoma patients receiving concurrent chemoradiotherapy: A population-based propensity score matched analysis

https://doi.org/10.18632/oncotarget.12250

Chia-Chin Li, Chih-Yi Chen,  and Chun-Ru Chien
71548-71555
Abstract  |  PDF  |  HTML  |  How to cite

Long noncoding RNA uc.345 promotes tumorigenesis of pancreatic cancer by upregulation of hnRNPL expression

Long noncoding RNA uc.345 promotes tumorigenesis of pancreatic cancer by upregulation of hnRNPL expression

https://doi.org/10.18632/oncotarget.12253

Chao Liu, Jiamin Wang, Xiaoyuan Yuan, Wenli Qian, Bosen Zhang, Minmin Shi, Junjie Xie, Baiyong Shen, Hong Xu, Zhaoyuan Hou,  and Hao Chen
71556-71566
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Integration of zebrafish fin regeneration genes with expression data of human tumors in silico uncovers potential novel melanoma markers

Integration of zebrafish fin regeneration genes with expression data of human tumors in silico uncovers potential novel melanoma markers

https://doi.org/10.18632/oncotarget.12257

Martin Hagedorn, Géraldine Siegfried, Katarzyna B. Hooks,  and Abdel-Majid Khatib
71567-71579
Abstract  |  PDF  |  HTML  |  How to cite

Blockade of the Hedgehog pathway downregulates estrogen receptor alpha signaling in breast cancer cells

Blockade of the Hedgehog pathway downregulates estrogen receptor alpha signaling in breast cancer cells

https://doi.org/10.18632/oncotarget.12259

Yumei Diao, Ani Azatyan, Mohammed Ferdous-Ur Rahman, Chunyan Zhao, Jian Zhu, Karin Dahlman-Wright,  and Peter G. Zaphiropoulos
71580-71593
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

In vivo phage display screening for tumor vascular targets in glioblastoma identifies a llama nanobody against dynactin-1-p150Glued

In vivo phage display screening for tumor vascular targets in glioblastoma identifies a llama nanobody against dynactin-1-p150Glued

https://doi.org/10.18632/oncotarget.12261

Sanne A.M. van Lith, Ilse Roodink, Joost J.C. Verhoeff, Petri I. Mäkinen, Jari P. Lappalainen, Seppo Ylä-Herttuala, Jos Raats, Erwin van Wijk, Ronald Roepman, Stef J. Letteboer, Kiek Verrijp,  and William P.J. Leenders
71594-71607
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Progressive changes in composition of lymphocytes in lung tissues from patients with non-small-cell lung cancer

Progressive changes in composition of lymphocytes in lung tissues from patients with non-small-cell lung cancer

https://doi.org/10.18632/oncotarget.12264

María del Mar Valenzuela-Membrives, Francisco Perea-García, Abel Sanchez-Palencia, Francisco Ruiz-Cabello, Mercedes Gómez-Morales, María Teresa Miranda-León, Inmaculada Galindo-Angel,  and María Esther Fárez-Vidal
71608-71619
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Identification of novel prognostic indicators for triple-negative breast cancer patients through integrative analysis of cancer genomics data and protein interactome data

Identification of novel prognostic indicators for triple-negative breast cancer patients through integrative analysis of cancer genomics data and protein interactome data

https://doi.org/10.18632/oncotarget.12287

Fan Zhang, Chunyan Ren, Hengqiang Zhao, Lei Yang, Fei Su, Ming-Ming Zhou, Junwei Han, Eric A. Sobie,  and Martin J. Walsh
71620-71634
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential

Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential

https://doi.org/10.18632/oncotarget.11928

Jason J. Kwon, Jeffrey A. Willy, Kayla A. Quirin, Ronald C. Wek, Murray Korc, Xiao-Ming Yin,  and Janaiah Kota
71635-71650
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

The p53 status can influence the role of Sam68 in tumorigenesis

The p53 status can influence the role of Sam68 in tumorigenesis

https://doi.org/10.18632/oncotarget.12305

Naomi Li, Chau Tuan-Anh Ngo, Olga Aleynikova, Nicole Beauchemin,  and Stéphane Richard
71651-71659
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MK-8776, a novel chk1 kinase inhibitor, radiosensitizes p53-defective human tumor cells

MK-8776, a novel chk1 kinase inhibitor, radiosensitizes p53-defective human tumor cells

https://doi.org/10.18632/oncotarget.12311

Kathleen A. Bridges, Xingxing Chen, Huifeng Liu, Crosby Rock, Thomas A. Buchholz, Stuart D. Shumway, Heath D. Skinner,  and Raymond E. Meyn
71660-71672
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

IL-10 secreted by M2 macrophage promoted tumorigenesis through interaction with JAK2 in glioma

IL-10 secreted by M2 macrophage promoted tumorigenesis through interaction with JAK2 in glioma

https://doi.org/10.18632/oncotarget.12317

Ling Qi, Hongquan Yu, Yu Zhang, Donghai Zhao, Peng Lv, Yue Zhong,  and Ye Xu
71673-71685
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Prevalence of actionable mutations and copy number alterations and the price of a genomic testing panel

Prevalence of actionable mutations and copy number alterations and the price of a genomic testing panel

https://doi.org/10.18632/oncotarget.11994

Chan Shen, Funda Meric-Bernstam, Xiaoping Su, John Mendelsohn,  and Sharon Giordano
71686-71695
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy

Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy

https://doi.org/10.18632/oncotarget.12322

Yukihiko Hiroshima, Ali Maawy, Yong Zhang, Nan Zhang, Takashi Murakami, Takashi Chishima, Kuniya Tanaka, Yasushi Ichikawa, Michael Bouvet, Itaru Endo,  and Robert M. Hoffman
71696-71702
Abstract  |  PDF  |  HTML  |  How to cite

Gene polymorphisms are associated with clinical outcome in Chinese resected laryngeal carcinoma patients

Gene polymorphisms are associated with clinical outcome in Chinese resected laryngeal carcinoma patients

https://doi.org/10.18632/oncotarget.12323

Peng Chen, Zhengshuai Chen, Jinglie Li, Hua Yang, Yuanyuan Zhu, Ning Zhang, Mengdan Yan, Yuan Shao, Chao Chen,  and Tianbo Jin
71703-71709
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Fiber-modified adenovirus-mediated suicide gene therapy can efficiently eliminate bladder cancer cells in vitro and in vivo

Fiber-modified adenovirus-mediated suicide gene therapy can efficiently eliminate bladder cancer cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.12324

De-Gui Wang, Mei-Jun Zhao, Yong-Qiang Liu, Xiang-Wen Liu, Hai-Tao Niu, Yan-Feng Song,  and Ying-Xia Tian
71710-71717
Abstract  |  PDF  |  HTML  |  How to cite

MDM4 rs4245739 A > C polymorphism correlates with reduced overall cancer risk in a meta-analysis of 69477 subjects

MDM4 rs4245739 A > C polymorphism correlates with reduced overall cancer risk in a meta-analysis of 69477 subjects

https://doi.org/10.18632/oncotarget.12326

Chaoyi Xu, Jinhong Zhu, Wen Fu, Zongwen Liang, Shujie Song, Yuan Zhao, Lihua Lyu, Anqi Zhang, Jing He,  and Ping Duan
71718-71726
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Correlation of neuroendocrine features with prognosis of non-small cell lung cancer

Correlation of neuroendocrine features with prognosis of non-small cell lung cancer

https://doi.org/10.18632/oncotarget.12327

Jianguo Feng, Huaying Sheng, Chihong Zhu, Xiaoqian Qian, Danying Wan, Dan Su, Zhu Liming,  and Liming Zhu
71727-71736
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model

Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model

https://doi.org/10.18632/oncotarget.12328

Kei Kawaguchi, Takashi Murakami, Bartosz Chmielowski, Kentaro Igarashi, Tasuku Kiyuna, Michiaki Unno, Scott D. Nelson, Tara A. Russell, Sarah M. Dry, Yunfeng Li, Fritz C. Eilber,  and Robert M. Hoffman
71737-71743
Abstract  |  PDF  |  HTML  |  How to cite

RAB22A overexpression promotes the tumor growth of melanoma

RAB22A overexpression promotes the tumor growth of melanoma

https://doi.org/10.18632/oncotarget.12329

Feng Su, Yifei Chen, Shilin Zhu, Fangfang Li, Shuang Zhao, Lisa Wu, Xiang Chen,  and Juan Su
71744-71753
Abstract  |  PDF  |  HTML  |  How to cite

Myricetin, a potent natural agent for treatment of diabetic skin damage by modulating TIMP/MMPs balance and oxidative stress

Myricetin, a potent natural agent for treatment of diabetic skin damage by modulating TIMP/MMPs balance and oxidative stress

https://doi.org/10.18632/oncotarget.12330

Zijian Wu, Xuemin Zheng, Min Gong,  and Ying Li
71754-71760
Abstract  |  PDF  |  HTML  |  How to cite

Novel nomograms for survival and progression in HPV+ and HPV- oropharyngeal cancer: a population-based study of 1,542 consecutive patients

Novel nomograms for survival and progression in HPV+ and HPV- oropharyngeal cancer: a population-based study of 1,542 consecutive patients

https://doi.org/10.18632/oncotarget.12335

Christian Grønhøj Larsen, David H. Jensen, Amanda-Louise Fenger Carlander, Katalin Kiss, Luise Andersen, Caroline Holkmann Olsen, Elo Andersen, Emilie Garnæs, Finn Cilius, Lena Specht,  and Christian von Buchwald
71761-71772
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer

Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer

https://doi.org/10.18632/oncotarget.12365

Le Li, Guang-Quan Zhang, Hua Chen, Zhong-Jie Zhao, Hong-Ze Chen, Huan Liu, Gang Wang, Yue-Hui Jia, Shang-Ha Pan, Rui Kong, Yong-Wei Wang,  and Bei Sun
71773-71781
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Early responses of EGFR circulating tumor DNA to EGFR tyrosine kinase inhibitors in lung cancer treatment

Early responses of EGFR circulating tumor DNA to EGFR tyrosine kinase inhibitors in lung cancer treatment

https://doi.org/10.18632/oncotarget.12373

Fumio Imamura, Junji Uchida, Yoji Kukita, Toru Kumagai, Kazumi Nishino, Takako Inoue, Madoka Kimura,  and Kikuya Kato
71782-71789
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

JWA down-regulates HER2 expression via c-Cbl and induces lapatinib resistance in human gastric cancer cells

JWA down-regulates HER2 expression via c-Cbl and induces lapatinib resistance in human gastric cancer cells

https://doi.org/10.18632/oncotarget.12374

Ling Ma, Weiyou Zhu, Qiang Wang, Fengming Yang, Jing Qian, Tongpeng Xu, Shouyu Wang, Jianwei Zhou,  and Yongqian Shu
71790-71801
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Hypoxia pathway and hypoxia-mediated extensive extramedullary hematopoiesis are involved in ursolic acid’s anti-metastatic effect in 4T1 tumor bearing mice

Hypoxia pathway and hypoxia-mediated extensive extramedullary hematopoiesis are involved in ursolic acid’s anti-metastatic effect in 4T1 tumor bearing mice

https://doi.org/10.18632/oncotarget.12375

Jian-Li Gao, Yan-Mei Shui, Wei Jiang, En-Yi Huang, Qi-Yang Shou, Xin Ji, Bai-Cheng He, Gui-Yuan Lv,  and Tong-Chuan He
71802-71816
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Chronic low-dose-rate ionising radiation affects the hippocampal phosphoproteome in the ApoE−/− Alzheimer's mouse model

Chronic low-dose-rate ionising radiation affects the hippocampal phosphoproteome in the ApoE−/− Alzheimer's mouse model

https://doi.org/10.18632/oncotarget.12376

Stefan J. Kempf, Dirk Janik, Zarko Barjaktarovic, Ignacia Braga-Tanaka III, Satoshi Tanaka, Frauke Neff, Anna Saran, Martin R. Larsen,  and Soile Tapio
71817-71832
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

A novel DNA methylation score accurately predicts death from prostate cancer in men with low to intermediate clinical risk factors

A novel DNA methylation score accurately predicts death from prostate cancer in men with low to intermediate clinical risk factors

https://doi.org/10.18632/oncotarget.12377

Amar S. Ahmad, Nataša Vasiljević, Paul Carter, Daniel M Berney, Henrik Møller, Christopher S. Foster, Jack Cuzick,  and Attila T. Lorincz
71833-71840
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Scriptaid overcomes hypoxia-induced cisplatin resistance in both wild-type and mutant p53 lung cancer cells

Scriptaid overcomes hypoxia-induced cisplatin resistance in both wild-type and mutant p53 lung cancer cells

https://doi.org/10.18632/oncotarget.12378

Shrikant Pradhan, Divyank Mahajan, Prabhjot Kaur, Namita Pandey, Chandresh Sharma,  and Tapasya Srivastava
71841-71855
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Distinct biological effects of low-dose radiation on normal and cancerous human lung cells are mediated by ATM signaling

Distinct biological effects of low-dose radiation on normal and cancerous human lung cells are mediated by ATM signaling

https://doi.org/10.18632/oncotarget.12379

Guozi Yang, Dehai Yu, Wei Li, Yuguang Zhao, Xue Wen, Xinyue Liang, Xiaoying Zhang, Lei Zhou, Jifan Hu, Chao Niu, Huimin Tian, Fujun Han, Xiao Chen, Lihua Dong, Lu Cai,  and Jiuwei Cui
71856-71872
Abstract  |  PDF  |  HTML  |  How to cite

Downregulation of sphingosine kinase-1 induces protective tumor immunity by promoting M1 macrophage response in melanoma

Downregulation of sphingosine kinase-1 induces protective tumor immunity by promoting M1 macrophage response in melanoma

https://doi.org/10.18632/oncotarget.12380

Marguerite Mrad, Caroline Imbert, Virginie Garcia, Florian Rambow, Nicole Therville, Stéphane Carpentier, Bruno Ségui, Thierry Levade, Rania Azar, Jean-Christophe Marine, Mona Diab-Assaf, Céline Colacios,  and Nathalie Andrieu-Abadie
71873-71886
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Receptor conversion in metastatic breast cancer: a prognosticator of survival

Receptor conversion in metastatic breast cancer: a prognosticator of survival

https://doi.org/10.18632/oncotarget.12114

Xiangying Meng, Santai Song, Ze-Fei Jiang, Bing Sun, Tao Wang, Shaohua Zhang,  and Shikai Wu
71887-71903
Abstract  |  PDF  |  HTML  |  How to cite

MDS shows a higher expression of hTERT and alternative splice variants in unactivated T-cells

MDS shows a higher expression of hTERT and alternative splice variants in unactivated T-cells

https://doi.org/10.18632/oncotarget.12115

Wen Dong, Lei Wu, Houfang Sun, Xiubao Ren, Pearlie K. Epling-Burnette,  and Lili Yang
71904-71914
Abstract  |  PDF  |  HTML  |  How to cite

Automated analysis of acute myeloid leukemia minimal residual disease using a support vector machine

Automated analysis of acute myeloid leukemia minimal residual disease using a support vector machine

https://doi.org/10.18632/oncotarget.12430

Wanmao Ni, Beili Hu, Cuiping Zheng, Yin Tong, Lei Wang, Qing-qing Li, Xiangmin Tong,  and Yong Han
71915-71921
Abstract  |  PDF  |  HTML  |  How to cite

MicroRNA-130a alleviates human coronary artery endothelial cell injury and inflammatory responses by targeting PTEN via activating PI3K/Akt/eNOS signaling pathway

MicroRNA-130a alleviates human coronary artery endothelial cell injury and inflammatory responses by targeting PTEN via activating PI3K/Akt/eNOS signaling pathway

https://doi.org/10.18632/oncotarget.12431

Chun-Li Song, Bin Liu, Yong-Feng Shi, Ning Liu, You-You Yan, Ji-Chang Zhang, Xin Xue, Jin-Peng Wang, Zhuo Zhao, Jian-Gen Liu, Yang-Xue Li, Xiao-Hao Zhang,  and Jun-Duo Wu
71922-71936
Abstract  |  PDF  |  HTML  |  How to cite

Depletion of pro-oncogenic RUNX2 enhances gemcitabine (GEM) sensitivity of p53-mutated pancreatic cancer Panc-1 cells through the induction of pro-apoptotic TAp63

Depletion of pro-oncogenic RUNX2 enhances gemcitabine (GEM) sensitivity of p53-mutated pancreatic cancer Panc-1 cells through the induction of pro-apoptotic TAp63

https://doi.org/10.18632/oncotarget.12433

Toshinori Ozaki, Mizuyo Nakamura, Takehiro Ogata, Meijie Sang, Hiroyuki Yoda, Kiriko Hiraoka, Meixiang Sang,  and Osamu Shimozato
71937-71950
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Secondary malignancies after partial versus whole breast irradiation: a systematic review and meta-analysis

Secondary malignancies after partial versus whole breast irradiation: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.12442

Xin-Bin Pan, Shi-Ting Huang, Yan-Ming Jiang, Jia-Lin Ma,  and Xiao-Dong Zhu
71951-71959
Abstract  |  PDF  |  HTML  |  How to cite

18β-glycyrrhetinic acid suppresses gastric cancer by activation of miR-149-3p-Wnt-1 signaling

18β-glycyrrhetinic acid suppresses gastric cancer by activation of miR-149-3p-Wnt-1 signaling

https://doi.org/10.18632/oncotarget.12443

Donghui Cao, Zhifang Jia, Lili You, Yanhua Wu, Zhen Hou, Yueer Suo, Houjun Zhang, Simin Wen, Tetsuya Tsukamoto, Masanobu Oshima, Jing Jiang,  and Xueyuan Cao
71960-71973
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Induction treatments for acute promyelocytic leukemia: a network meta-analysis

Induction treatments for acute promyelocytic leukemia: a network meta-analysis

https://doi.org/10.18632/oncotarget.12451

Junjie Huang, Min Sun, Zitong Wang, Qiaoxia Zhang, Jin Lou, Yun Cai, Weihong Chen,  and Xin Du
71974-71986
Abstract  |  PDF  |  HTML  |  How to cite

Spc24 is required for meiotic kinetochore-microtubule attachment and production of euploid eggs

Spc24 is required for meiotic kinetochore-microtubule attachment and production of euploid eggs

https://doi.org/10.18632/oncotarget.12453

Teng Zhang, Yang Zhou, Hong-Hui Wang, Tie-Gang Meng, Lei Guo, Xue-Shan Ma, Wei Shen, Heide Schatten,  and Qing-Yuan Sun
71987-71997
Abstract  |  PDF  |  HTML  |  How to cite

New strategy to rescue the inhibition of osteogenesis of human bone marrow-derived mesenchymal stem cells under oxidative stress: combination of vitamin C and graphene foams

New strategy to rescue the inhibition of osteogenesis of human bone marrow-derived mesenchymal stem cells under oxidative stress: combination of vitamin C and graphene foams

https://doi.org/10.18632/oncotarget.12456

Zubin Zhou, Zhengliang Xu, Feng Wang, Ye Lu, Peipei Yin, Chaolai Jiang, Yingjie Liu, Hua Li, Xiaowei Yu,  and Yuqiang Sun
71998-72010
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Increased gene expression noise in human cancers is correlated with low p53 and immune activities as well as late stage cancer

Increased gene expression noise in human cancers is correlated with low p53 and immune activities as well as late stage cancer

https://doi.org/10.18632/oncotarget.12457

Rongfei Han, Guanqun Huang, Yejun Wang, Yafei Xu, Yueming Hu, Wenqi Jiang, Tianfu Wang, Tian Xiao,  and Duo Zheng
72011-72020
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Discovery of cell surface vimentin targeting mAb for direct disruption of GBM tumor initiating cells

Discovery of cell surface vimentin targeting mAb for direct disruption of GBM tumor initiating cells

https://doi.org/10.18632/oncotarget.12458

Hyangsoon Noh, Jun Yan, Sungguan Hong, Ling-Yuan Kong, Konrad Gabrusiewicz, Xueqing Xia, Amy B. Heimberger,  and Shulin Li
72021-72032
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Highly elevated serum lactate dehydrogenase is associated with central nervous system relapse in patients with diffuse large B-cell lymphoma: Results of a multicenter prospective cohort study

Highly elevated serum lactate dehydrogenase is associated with central nervous system relapse in patients with diffuse large B-cell lymphoma: Results of a multicenter prospective cohort study

https://doi.org/10.18632/oncotarget.12459

Seok Jin Kim, Jun Sik Hong, Myung Hee Chang, Jeong-A Kim, Jae-Yong Kwak, Jin Seok Kim, Dok Hyun Yoon, Won Sik Lee, Young Rok Do, Hye Jin Kang, Hyeon-Seok Eom, Yong Park, Jong-Ho Won, Yeung-Chul Mun, Hyo Jung Kim, Jung Hye Kwon, Jee Hyun Kong, Sung Yong Oh, Sunah Lee, Sung Hwa Bae, Deok-Hwan Yang, Hyun Jung Jun, Yang Soo Kim, Hwan Jung Yun, Soon Il Lee, Min Kyoung Kim, Eun Kyung Park, Won Seog Kim,  and Cheolwon Suh
72033-72043
Abstract  |  PDF  |  HTML  |  How to cite

Improved outcome in acute myeloid leukemia patients enrolled in clinical trials: A national population-based cohort study of Danish intensive chemotherapy patients

Improved outcome in acute myeloid leukemia patients enrolled in clinical trials: A national population-based cohort study of Danish intensive chemotherapy patients

https://doi.org/10.18632/oncotarget.12495

Lene Sofie Granfeldt Østgård, Mette Nørgaard, Henrik Sengeløv, Bruno C. Medeiros, Lars Kjeldsen, Ulrik Malthe Overgaard, Marianne Tang Severinsen, Claus Werenberg Marcher, Morten Krogh Jensen,  and Jan Maxwell Nørgaard
72044-72056
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Is alkaline phosphatase the smoking gun for highly refractory primitive leukemic cells?

Is alkaline phosphatase the smoking gun for highly refractory primitive leukemic cells?

https://doi.org/10.18632/oncotarget.12497

Laura G. Rico, Jordi Juncà, Mike D. Ward, Jolene Bradford,  and Jordi Petriz
72057-72066
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

miR-202 inhibits the progression of human cervical cancer through inhibition of cyclin D1

miR-202 inhibits the progression of human cervical cancer through inhibition of cyclin D1

https://doi.org/10.18632/oncotarget.12499

Yuexiong Yi, Huirong Li, Qiongying Lv, Kejia Wu, Wenfen Zhang, Juan Zhang, Dingjun Zhu, Qing Liu,  and Wei Zhang
72067-72075
Abstract  |  PDF  |  HTML  |  How to cite

Preoperative combined hemoglobin, albumin, lymphocyte and platelet levels predict survival in patients with locally advanced colorectal cancer

Preoperative combined hemoglobin, albumin, lymphocyte and platelet levels predict survival in patients with locally advanced colorectal cancer

https://doi.org/10.18632/oncotarget.12271

Huihong Jiang, Huaguang Li, Ajian Li, Erjiang Tang, Dan Xu, Yin Chen, Yong Zhang, Min Tang, Zhiyong Zhang, Xiaxing Deng,  and Moubin Lin
72076-72083
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p) coordinately targeted MTDH in lung squamous cell carcinoma

Dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p) coordinately targeted MTDH in lung squamous cell carcinoma

https://doi.org/10.18632/oncotarget.12290

Hiroko Mataki, Naohiko Seki, Keiko Mizuno, Nijiro Nohata, Kazuto Kamikawaji, Tomohiro Kumamoto, Keiichi Koshizuka, Yusuke Goto,  and Hiromasa Inoue
72084-72098
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Receptor tyrosine kinase amplified gastric cancer: Clinicopathologic characteristics and proposed screening algorithm

Receptor tyrosine kinase amplified gastric cancer: Clinicopathologic characteristics and proposed screening algorithm

https://doi.org/10.18632/oncotarget.12291

Cheol Keun Park, Ji Soo Park, Hyo Song Kim, Sun Young Rha, Woo Jin Hyung, Jae-Ho Cheong, Sung Hoon Noh, Sang Kil Lee, Yong Chan Lee, Yong-min Huh,  and Hyunki Kim
72099-72112
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity

Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity

https://doi.org/10.18632/oncotarget.12350

Takayuki Kishi, Taira Mayanagi, Sadahiro Iwabuchi, Toshihide Akasaka,  and Kenji Sobue
72113-72130
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma

PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.12351

Hao Yang, Xiaoping Zhao, Li Zhao, Liu Liu, Jiajin Li, Wenzhi Jia, Jianjun Liu,  and Gang Huang
72131-72147
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

NSAID-activated gene 1 mediates pro-inflammatory signaling activation and paclitaxel chemoresistance in type I human epithelial ovarian cancer stem-like cells

NSAID-activated gene 1 mediates pro-inflammatory signaling activation and paclitaxel chemoresistance in type I human epithelial ovarian cancer stem-like cells

https://doi.org/10.18632/oncotarget.12355

Ki-Hyung Kim, Seong-Hwan Park, Kee Hun Do, Juil Kim, Kyung Un Choi,  and Yuseok Moon
72148-72166
Abstract  |  PDF  |  HTML  |  How to cite

A module of inflammatory cytokines defines resistance of colorectal cancer to EGFR inhibitors

A module of inflammatory cytokines defines resistance of colorectal cancer to EGFR inhibitors

https://doi.org/10.18632/oncotarget.12354

Valerio Gelfo, Maria Teresa Rodia, Michela Pucci, Massimiliano Dall’Ora, Spartaco Santi, Rossella Solmi, Lee Roth, Moshit Lindzen, Massimiliano Bonafè, Andrea Bertotti, Elisabetta Caramelli, Pier-Luigi Lollini, Livio Trusolino, Yosef Yarden, Gabriele D’Uva,  and Mattia Lauriola
72167-72183
Abstract  |  PDF  |  HTML  |  How to cite

Prognostic effect of intratumoral neutrophils across histological subtypes of non-small cell lung cancer

Prognostic effect of intratumoral neutrophils across histological subtypes of non-small cell lung cancer

https://doi.org/10.18632/oncotarget.12360

Mehrdad Rakaee, Lill-Tove Busund, Erna-Elise Paulsen, Elin Richardsen, Samer Al-Saad, Sigve Andersen, Tom Donnem, Roy M. Bremnes,  and Thomas K. Kilvaer
72184-72196
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

A strong host response and lack of MYC expression are characteristic for diffuse large B cell lymphoma transformed from nodular lymphocyte predominant Hodgkin lymphoma

A strong host response and lack of MYC expression are characteristic for diffuse large B cell lymphoma transformed from nodular lymphocyte predominant Hodgkin lymphoma

https://doi.org/10.18632/oncotarget.12363

Bianca Schuhmacher, Benjamin Rengstl, Claudia Döring, Julia Bein, Sebastian Newrzela, Uta Brunnberg, Hans Michael Kvasnicka, Martine Vornanen, Ralf Küppers, Martin-Leo Hansmann,  and Sylvia Hartmann
72197-72210
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Evaluation of the anatomical parameters for normal tissue sparing in the prone position radiotherapy with small sized left breasts

Evaluation of the anatomical parameters for normal tissue sparing in the prone position radiotherapy with small sized left breasts

https://doi.org/10.18632/oncotarget.12662

Hyunjung Kim,  and Jinyoung Kim
72211-72218
Abstract  |  PDF  |  HTML  |  How to cite

Prognostic value of pretreatment serum beta-2 microglobulin level in advanced classical Hodgkin lymphoma treated in the modern era

Prognostic value of pretreatment serum beta-2 microglobulin level in advanced classical Hodgkin lymphoma treated in the modern era

https://doi.org/10.18632/oncotarget.12663

Qin Wang, Yan Qin, Shengyu Zhou, Xiaohui He, Jianliang Yang, Suyi Kang, Peng Liu, Sheng Yang, Changgong Zhang, Lin Gui, Yuankai Shi,  and Yuankai Shi
72219-72228
Abstract  |  PDF  |  HTML  |  How to cite

Filamin A interacting protein 1-like expression inhibits progression in colorectal cancer

Filamin A interacting protein 1-like expression inhibits progression in colorectal cancer

https://doi.org/10.18632/oncotarget.12664

Young-Lan Park, Sun-Young Park, Seung-Hyun Lee, Rul-Bin Kim, Joong-Keun Kim, Sung-Yoon Rew, Dae-Seong Myung, Sung-Bum Cho, Wan-Sik Lee, Hyun-Soo Kim,  and Young-Eun Joo
72229-72241
Abstract  |  PDF  |  HTML  |  How to cite

Prognostic significance of B7-H4 expression in matched primary pancreatic cancer and liver metastases

Prognostic significance of B7-H4 expression in matched primary pancreatic cancer and liver metastases

https://doi.org/10.18632/oncotarget.12665

Yun Qian, Yiwen Sang, Frederick X.C. Wang, Bo Hong, Qi Wang, Xinhui Zhou, Tianhao Weng, Zhigang Wu, Min Zheng, Hong Zhang,  and Hangping Yao
72242-72249
Abstract  |  PDF  |  HTML  |  How to cite

Ino80 promotes cervical cancer tumorigenesis by activating Nanog expression

Ino80 promotes cervical cancer tumorigenesis by activating Nanog expression

https://doi.org/10.18632/oncotarget.12667

Jing Hu, Jie Liu, Aozheng Chen, Jia Lyu, Guihai Ai, Qiongjing Zeng, Yi Sun, Chunxia Chen, Jinbo Wang, Jin Qiu, Yi Wu, Jiajing Cheng, Xiujuan Shi,  and Liwen Song
72250-72262
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Clinical Research Papers

The role of surgical intervention in primary colorectal lymphoma: A SEER population-based analysis

The role of surgical intervention in primary colorectal lymphoma: A SEER population-based analysis

https://doi.org/10.18632/oncotarget.12344

Yi-bo Cai, Hai-yan Chen, Jin-jie He, Ye-ting Hu, Qi Yang, Liu-bo Chen, Qian Xiao,  and Ke-feng Ding
72263-72275
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Prognostic significance of preoperative aspartate aminotransferase to neutrophil ratio index in patients with hepatocellular carcinoma after hepatic resection

Prognostic significance of preoperative aspartate aminotransferase to neutrophil ratio index in patients with hepatocellular carcinoma after hepatic resection

https://doi.org/10.18632/oncotarget.10848

Fei Ji, Shunjun Fu, Zhiyong Guo, Hui Pang, Dubo Chen, Xiaoping Wang, Weiqiang Ju, Dongping Wang, Xiaoshun He, Yunpeng Hua,  and Baogang Peng
72276-72289
Abstract  |  PDF  |  HTML  |  How to cite

Negative to positive lymph node ratio is a superior predictor than traditional lymph node status in stage III colorectal cancer

Negative to positive lymph node ratio is a superior predictor than traditional lymph node status in stage III colorectal cancer

https://doi.org/10.18632/oncotarget.10806

Qingguo Li, Lei Liang, Huixun Jia, Xinxiang Li, Ye Xu, Ji Zhu,  and Sanjun Cai
72290-72299
Abstract  |  PDF  |  HTML  |  How to cite

A new predictive model combined of tumor size, lymph nodes count and lymphovascular invasion for survival prognosis in patients with lymph node-negative gastric cancer

A new predictive model combined of tumor size, lymph nodes count and lymphovascular invasion for survival prognosis in patients with lymph node-negative gastric cancer

https://doi.org/10.18632/oncotarget.11035

Lin-Yong Zhao, Xiao-Long Chen, Yi-Gao Wang, Yue Xin, Wei-Han Zhang, Yin-Su Wang, Xin-Zu Chen, Kun Yang, Kai Liu, Lian Xue, Bo Zhang, Zhi-Xin Chen, Jia-Ping Chen, Zong-Guang Zhou,  and Jian-Kun Hu
72300-72310
Abstract  |  PDF  |  HTML  |  How to cite

Genetic predisposition and induced pro-inflammatory/pro-oxidative status may play a role in increased atherothrombotic events in nilotinib treated chronic myeloid leukemia patients

Genetic predisposition and induced pro-inflammatory/pro-oxidative status may play a role in increased atherothrombotic events in nilotinib treated chronic myeloid leukemia patients

https://doi.org/10.18632/oncotarget.11100

Monica Bocchia, Sara Galimberti, Lara Aprile, Anna Sicuranza, Antonella Gozzini, Francesca Santilli, Elisabetta Abruzzese, Claudia Baratè, Barbara Scappini, Giulia Fontanelli, Monika Malgorzata Trawinska, Marzia Defina, Alessandro Gozzetti, Alberto Bosi, Mario Petrini,  and Luca Puccetti
72311-72321
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Reviews

Addressing intra-tumoral heterogeneity and therapy resistance

Addressing intra-tumoral heterogeneity and therapy resistance

https://doi.org/10.18632/oncotarget.11875

Brad Rybinski,  and Kyuson Yun
72322-72342
Abstract  |  PDF  |  HTML  |  How to cite

Trans-arterial radioembolization in intermediate-advanced hepatocellular carcinoma: systematic review and meta-analyses

Trans-arterial radioembolization in intermediate-advanced hepatocellular carcinoma: systematic review and meta-analyses

https://doi.org/10.18632/oncotarget.11644

Carla Rognoni, Oriana Ciani, Silvia Sommariva, Antonio Facciorusso, Rosanna Tarricone, Sherrie Bhoori,  and Vincenzo Mazzaferro
72343-72355
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Sex chromosome loss and the pseudoautosomal region genes in hematological malignancies

Sex chromosome loss and the pseudoautosomal region genes in hematological malignancies

https://doi.org/10.18632/oncotarget.12050

Stephanie Weng, Samuel A. Stoner,  and Dong-Er Zhang
72356-72372
Abstract  |  PDF  |  HTML  |  How to cite

Case Reports

Response to apatinib in chemotherapy-failed advanced spindle cell breast carcinoma

Response to apatinib in chemotherapy-failed advanced spindle cell breast carcinoma

https://doi.org/10.18632/oncotarget.12568

Na Zhou, Congmin Liu, Helei Hou, Chuantao Zhang, Dong Liu, Guanqun Wang, Kewei Liu, Jingjuan Zhu, Hongying Lv, TianjJun Li,  and Xiaochun Zhang
72373-72379
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Corrections

Correction: 5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53

Correction: 5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53

https://doi.org/10.18632/oncotarget.12849

Birce Akpinar, Ethiene V. Bracht, Dorin Reijnders, Barbora Safarikova, Iva Jelinkova, Alf Grandien, Alena Hyrslova Vaculova, Boris Zhivotovsky,  and Magnus Olsson
72380-72380
Correction  |  PDF  |  How to cite


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