Sales for anti-angiogenic drugs

Exocytotic pore in a SNARE

Lysosomal regulation of cholesterol homeostasis in tuberous sclerosis complex is mediated via NPC1 and LDL-R

Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells

Elevated dietary magnesium during pregnancy and postnatal life prevents ectopic mineralization in Enpp1^asj mice, a model for generalized arterial calcification of infancy

Dietary capsaicin and antibiotics act synergistically to reduce non-alcoholic fatty liver disease induced by high fat diet in mice

Mutation of the Sp1 binding site in the 5’ flanking region of SRY causes sex reversal in rabbits

Alpha-ketoglutarate (AKG) lowers body weight and affects intestinal innate immunity through influencing intestinal microbiota

Selective elimination of long INterspersed element-1 expressing tumour cells by targeted expression of the HSV-TK suicide gene

Erythropoietin drives breast cancer progression by activation of its receptor EPOR

Lipid degradation promotes prostate cancer cell survival

Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma

CD24 Expression and differential resistance to chemotherapy in triple-negative breast cancer

Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines

Loss of tumour-specific ATM protein expression is an independent prognostic factor in early resected NSCLC

Development of [¹¹C]vemurafenib employing a carbon-11 carbonylative Stille coupling and preliminary evaluation in mice bearing melanoma tumor xenografts

Histone hypoacetylation contributes to CXCL12 downregulation in colon cancer: impact on tumor growth and cell migration

The associations of genetic polymorphisms in CYP1A2 and CYP3A4 with clinical outcomes of breast cancer patients in northern China

Accumulation of myeloid-derived suppressor cells (MDSCs) induced by low levels of IL-6 correlates with poor prognosis in bladder cancer

Complementary utility of targeted next-generation sequencing and immunohistochemistry panels as a screening platform to select targeted therapy for advanced gastric cancer

Interaction of Epstein-Barr virus genes with human gastric carcinoma transcriptome

The value of MRI in evaluating the efficacy and complications with the treatment of intra-arterial chemotherapy for retinoblastoma

TAZ induces lung cancer stem cell properties and tumorigenesis by up-regulating ALDH1A1

Effects of AQP5 gene silencing on proliferation, migration and apoptosis of human glioma cells through regulating EGFR/ERK/ p38 MAPK signaling pathway

Genotype-phenotype correlations in Chinese von Hippel–Lindau disease patients

Synthesis, bioactivity, 3D-QSAR studies of novel dibenzofuran derivatives as PTP-MEG2 inhibitors

Apocynin attenuates left ventricular remodeling in diabetic rabbits

The value of FATS expression in predicting sensitivity to radiotherapy in breast cancer

Early detection of gastric cancer using global, genome-wide and IRF4, ELMO1, CLIP4 and MSC DNA methylation in endoscopic biopsies

Identification of urine biomarkers associated with lung adenocarcinoma

CYP genes in osteosarcoma: Their role in tumorigenesis, pulmonary metastatic microenvironment and treatment response

Metabolomics uncovers a link between inositol metabolism and osteosarcoma metastasis

Laminarin promotes anti-cancer immunity by the maturation of dendritic cells

Novel recombinant immunotoxin of EGFR specific nanobody fused with cucurmosin, construction and antitumor efficiency in vitro

Selective eradication of cancer cells by delivery of adenovirus-based toxins

Multiplexed gene expression profiling identifies the FGFR4 pathway as a novel biomarker in intrahepatic cholangiocarcinoma

Effects of TLR-2/NF-κB signaling pathway on the occurrence of degenerative knee osteoarthritis: an in vivo and in vitro study

The impact of receptor recycling on the exocytosis of αvβ3 integrin targeted gold nanoparticles

Quercetin delays postovulatory aging of mouse oocytes by regulating SIRT expression and MPF activity

A mathematical theory of the transcription repression (TR) therapy of cancer - whether and how it may work

Low-density lipoprotein receptor-related protein 6 is a novel coreceptor of protease-activated receptor-2 in the dynamics of cancer-associated β-catenin stabilization

RNA sequencing-based cell proliferation analysis across 19 cancers identifies a subset of proliferation-informative cancers with a common survival signature

Is there a prognostic value of tumor location among Chinese patients with colorectal cancer?

The TERT rs2736100 polymorphism increases cancer risk: A meta-analysis

Distribution patterns of 21-gene recurrence score in 980 Chinese estrogen receptor-positive, HER2-negative early breast cancer patients

Contributions of MET activation to BCR-ABL1 tyrosine kinase inhibitor resistance in chronic myeloid leukemia cells

Downregulation of Bmi1 in breast cancer stem cells suppresses tumor growth and proliferation

Krüppel-like factor 17 inhibits urokinase plasminogen activator gene expression to suppress cell invasion through the Src/p38/MAPK signaling pathway in human lung adenocarcinoma

Significance of PI3K/AKT signaling pathway in metastasis of esophageal squamous cell carcinoma and its potential as a target for anti-metastasis therapy

Estrogen enhances mismatch repair by induction of MLH1 expression via estrogen receptor-β

A consensus-hemagglutinin-based vaccine delivered by an attenuated Salmonella mutant protects chickens against heterologous H7N1 influenza virus

Early effective treatment of small pulmonary nodules with video-assisted thoracoscopic surgery combined with CT-guided dual-barbed hookwire localization

Metabolite marker discovery for the detection of bladder cancer by comparative metabolomics

Smad inhibitor induces CSC differentiation for effective chemosensitization in cyclin D1- and TGF-β/Smad-regulated liver cancer stem cell-like cells

MTA1 promotes epithelial to mesenchymal transition and metastasis in non-small-cell lung cancer

Expression of guanylyl cyclase C in tissue samples and the circulation of rectal cancer patients

The PD-1, PD-L1 expression and CD3+ T cell infiltration in relation to outcome in advanced gastric signet-ring cell carcinoma, representing a potential biomarker for immunotherapy

ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients

Contribution of macrophages in the contrast loss in iron oxide-based MRI cancer cell tracking studies

Syntenin promotes VEGF-induced VEGFR2 endocytosis and angiogenesis by increasing ephrin-B2 function in endothelial cells

A 3-miRNA signature predicts prognosis of pediatric and adolescent cytogenetically normal acute myeloid leukemia

Elevated serum A20 is associated with severity of chronic hepatitis B and A20 inhibits NF-κB-mediated inflammatory response

PEGylated PLGA-based phase shift nanodroplets combined with focused ultrasound for blood brain barrier opening in rats

DDX23-Linc00630-HDAC1 axis activates the Notch pathway to promote metastasis

Identification of eight genetic variants as novel determinants of dyslipidemia in Japanese by exome-wide association studies

Expression pattern of estroprogestinic receptors in sinonasal inverted papilloma

Prognostic value of IRF-2 expression in colorectal cancer

Pelvic reconstruction with different rod-screw systems following Enneking type I/I + IV resection: a clinical study

Antineoplastic effects of CPPTL via the ROS/JNK pathway in acute myeloid leukemia

Co-expression of AFAP1-AS1 and PD-1 predicts poor prognosis in nasopharyngeal carcinoma

Abce1 orchestrates M-phase entry and cytoskeleton architecture in mouse oocyte

CD47 promotes ovarian cancer progression by inhibiting macrophage phagocytosis

Wnt5a and CCL25 promote adult T-cell acute lymphoblastic leukemia cell migration, invasion and metastasis

CBX7 negatively regulates migration and invasion in glioma via Wnt/β-catenin pathway inactivation

Antiproliferative effect of ZSTK474 alone or in combination with chemotherapeutic drugs on HL60 and HL60/ADR cells

Prokaryotic expression of MLAA-34 and generation of a novel human ScFv against MLAA-34 by phage display technology

Cytochrome P450 1B1 inhibition suppresses tumorigenicity of prostate cancer via caspase-1 activation

A novel RON splice variant lacking exon 2 activates the PI3K/AKT pathway via PTEN phosphorylation in colorectal carcinoma cells

Combination GITR targeting/PD-1 blockade with vaccination drives robust antigen-specific antitumor immunity

Cofilin 1 induces the epithelial-mesenchymal transition of gastric cancer cells by promoting cytoskeletal rearrangement

Proton pump inhibitor ilaprazole suppresses cancer growth by targeting T-cell-originated protein kinase

IL-6R/STAT3/miR-204 feedback loop contributes to cisplatin resistance of epithelial ovarian cancer cells

Modeling therapeutic response to radioiodine in metastatic thyroid cancer: a proof-of-concept study for individualized medicine

The long noncoding RNA ANRIL acts as an oncogene and contributes to paclitaxel resistance of lung adenocarcinoma A549 cells

PDK1 inhibitor GSK2334470 exerts antitumor activity in multiple myeloma and forms a novel multitargeted combination with dual mTORC1/C2 inhibitor PP242

Programmed death-1 polymorphisms is associated with risk of esophagogastric junction adenocarcinoma in the Chinese Han population: A case-control study involving 2,740 subjects

Upregulation of minichromosome maintenance complex component 3 during epithelial-to-mesenchymal transition in human prostate cancer

The Bruton’s tyrosine kinase inhibitor ibrutinib exerts immunomodulatory effects through regulation of tumor-infiltrating macrophages

Targeting CCR2 with its antagonist suppresses viability, motility and invasion by downregulating MMP-9 expression in non-small cell lung cancer cells

The expression of histone deacetylase HDAC1 correlates with the progression and prognosis of gastrointestinal malignancy

Clinical genomic profiling to identify actionable alterations for investigational therapies in patients with diverse sarcomas

FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma

The SNAIL/miR-128 axis regulated growth, invasion, metastasis, and epithelial-to-mesenchymal transition of gastric cancer

Identification of rs7350481 at chromosome 11q23.3 as a novel susceptibility locus for metabolic syndrome in Japanese individuals by an exome-wide association study

PKC and CaMK-II inhibitions coordinately rescue ischemia-induced GABAergic neuron dysfunction

Trefoil factor 3 mediation of oncogenicity and chemoresistance in hepatocellular carcinoma is AKT-BCL-2 dependent

Elimination of LMP1-expressing cells from a monolayer of gastric cancer AGS cells

Simultaneous exposure to FcγR and FcαR on monocytes and macrophages enhances antitumor activity in vivo

Prognosis of stage III colorectal carcinomas with FOLFOX adjuvant chemotherapy can be predicted by molecular subtype

CSFV induced mitochondrial fission and mitophagy to inhibit apoptosis

OVOL2 antagonizes TGF-β signaling to regulate epithelial to mesenchymal transition during mammary tumor metastasis

A-to-I RNA editing of BLCAP lost the inhibition to STAT3 activation in cervical cancer

Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma

Dickkopf-related protein 2 induces G0/G1 arrest and apoptosis through suppressing Wnt/β-catenin signaling and is frequently methylated in breast cancer

Inhibition of exportin-1 function results in rapid cell cycle-associated DNA damage in cancer cells

GLUT1-mediated selective tumor targeting with fluorine containing platinum(II) glycoconjugates

Functional dissection of the role of UHRF1 in the regulation of retinoblastoma methylome

A topically-sprayable, activatable fluorescent and retaining probe, SPiDER-βGal for detecting cancer: Advantages of anchoring to cellular proteins after activation

Cancer stemness and metastatic potential of the novel tumor cell line K3: an inner mutated cell of bone marrow-derived mesenchymal stem cells

Platelet-derived growth factor receptor α in hepatocellular carcinoma is a prognostic marker independent of underlying liver cirrhosis

Nanoparticle-mediated dual delivery of resveratrol and DAP5 ameliorates kidney ischemia/reperfusion injury by inhibiting cell apoptosis and inflammation

Down-regulation of miR-29b in carcinoma associated fibroblasts promotes cell growth and metastasis of breast cancer

WISP-3 inhibition of miR-452 promotes VEGF-A expression in chondrosarcoma cells and induces endothelial progenitor cells angiogenesis

Genetic variation and forensic efficiency of autosomal insertion/deletion polymorphisms in Chinese Bai ethnic group: phylogenetic analysis to other populations

SIRT3-KLF15 signaling ameliorates kidney injury induced by hypertension

Overexpression of SphK2 contributes to ATRA resistance in colon cancer through rapid degradation of cytoplasmic RXRα by K48/K63-linked polyubiquitination

¹⁸F-fluorodeoxyglucose uptake predicts PKM2 expression in lung adenocarcinoma

Genetic rearrangements result in altered gene expression and novel fusion transcripts in Sézary syndrome

Pantoprazole blocks the JAK2/STAT3 pathway to alleviate skeletal muscle wasting in cancer cachexia by inhibiting inflammatory response

Clinicopathologic and prognostic significance of regulatory T cells in patients with hepatocellular carcinoma: a meta-analysis

Efficacy and safety comparison of chemotherapies for advanced gastric cancer: A network meta-analysis

Novel phenotypes of NF1 patients from unrelated Chinese families with tibial pseudarthrosis and anemia

Risk factors of locoregional relapse in locally advanced breast cancer treated with neoadjuvant chemotherapy following mastectomy and radiotherapy

Immunohistochemical profiling of receptor tyrosine kinases, MED12, and TGF-βRII of surgically resected small cell lung cancer, and the potential of c-kit as a prognostic marker

Tomotherapy as an adjuvant treatment for gastroesophageal junction and stomach cancer may reduce bowel and bone marrow toxicity compared to intensity-modulated radiotherapy and volumetric-modulated arc therapy

Diagnosis of cytomegalovirus pneumonia by quantitative polymerase chain reaction using bronchial washing fluid from patients with hematologic malignancies

Efficacy of transcatheter arterial chemoembolization for liver metastases arising from pancreatic cancer

Outcome and long-term efficacy of four facio-cervical fields conformal radiotherapy for nasopharyngeal carcinoma

Left ventricular longitudinal strain in soccer referees

Comparison between proton boron fusion therapy (PBFT) and boron neutron capture therapy (BNCT): a Monte Carlo study

Angiogenesis in NSCLC: is vessel co-option the trunk that sustains the branches?

Carfilzomib/pomalidomide single-agent or in combination with other agents for the management of relapsed/refractory multiple myeloma: a meta-analysis of 37 trials

Association between the BRCA2 rs144848 polymorphism and cancer susceptibility: a meta-analysis

A review and outlook in the treatment of osteosarcoma and other deep tumors with photodynamic therapy: from basic to deep

The serum 25-hydroxyvitamin D levels and hip fracture risk: a meta-analysis of prospective cohort studies

Roles of long noncoding RNAs in colorectal cancer metastasis

An exploration of the role of a fish-oriented diet in cognitive decline: a systematic review of the literature

Melatonin for the prevention and treatment of cancer

HIV-1 Tat inhibits EAAT-2 through AEG-1 upregulation in models of HIV-associated neurocognitive disorder

Correction: Th1^high in tumor microenvironment is an indicator of poor prognosis for patients with NSCLC