Salvage therapy for relapsed testicular cancer

Bioresorbable vascular scaffolds: between promises and reality

Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt’s lymphoma anti-tumor activity

Targeting MUC1-C suppresses polycomb repressive complex 1 in multiple myeloma

HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice

Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling

Loss of Egr1, a human del5q gene, accelerates BCR-ABL driven chronic myelogenous leukemia

Irreversible growth plate fusions in children with medulloblastoma treated with a targeted hedgehog pathway inhibitor

Wnt/β-catenin signaling promotes aging-associated hair graying in mice

Caloric restriction extends yeast chronological lifespan via a mechanism linking cellular aging to cell cycle regulation, maintenance of a quiescent state, entry into a non-quiescent state and survival in the non-quiescent state

HIF-1α:CRAT:miR-144-3p axis dysregulation promotes osteoarthritis chondrocyte apoptosis and VLCFA accumulation

Handgrip strength and subclinical carotid atherosclerosis in relation to platelet levels among hypertensive elderly Japanese

Astaxanthin acts via LRP-1 to inhibit inflammation and reverse lipopolysaccharide-induced M1/M2 polarization of microglial cells

Prox1 represses IL-2 gene expression by interacting with NFAT2

Proteomics analysis of bladder cancer invasion: Targeting EIF3D for therapeutic intervention

High number of chromosomal copy number aberrations inversely relates to t(11;19)(q21;p13) translocation status in mucoepidermoid carcinoma of the salivary glands

Triterpenoids from Aglaia abbreviata exert cytotoxicity and multidrug resistant reversal effect in MCF-7/ADM cells via reactive oxygen species induction and P-glycoprotein inhibition

BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma

Preclinical characterization of abemaciclib in hormone receptor positive breast cancer

Characterization of a novel androgen receptor (AR) coregulator RIPK1 and related chemicals that suppress AR-mediated prostate cancer growth via peptide and chemical screening

PDGFRA, HSD17B4 and HMGB2 are potential therapeutic targets in polycystic ovarian syndrome and breast cancer

Beneficial effect of fluoxetine treatment aganist psychological stress is mediated by increasing BDNF expression in selected brain areas

MiR-23a promotes TGF-β1-induced EMT and tumor metastasis in breast cancer cells by directly targeting CDH1 and activating Wnt/β-catenin signaling

Secreted miR-210-3p as non-invasive biomarker in clear cell renal cell carcinoma

HCaRG/COMMD5 inhibits ErbB receptor-driven renal cell carcinoma

Cross-talk mechanism between endothelial cells and hepatocellular carcinoma cells via growth factors and integrin pathway promotes tumor angiogenesis and cell migration

Identification of two novel biomarkers of rectal carcinoma progression and prognosis via co-expression network analysis

Mutation landscape and intra-tumor heterogeneity of two MANECs of the esophagus revealed by multi-region sequencing

ESE-1/ELF3 mRNA expression associates with poor survival outcomes in HER2⁺ breast cancer patients and is critical for tumorigenesis in HER2⁺ breast cancer cells

A potential panel of two-long non-coding RNA signature to predict recurrence of patients with laryngeal cancer

A phase I study of foretinib plus erlotinib in patients with previously treated advanced non-small cell lung cancer: Canadian cancer trials group IND.196

Progressive modulation of the human olfactory bulb transcriptome during Alzheimer´s disease evolution: novel insights into the olfactory signaling across proteinopathies

Clinicopathological characteristics and survival outcomes of male breast cancer according to race: A SEER population-based study

A small-molecule inhibitor targeting the AURKC–IκBα interaction decreases transformed growth of MDA-MB-231 breast cancer cells

Ethnic heterogeneity and prostate cancer mortality in Hispanic/Latino men: a population-based study

Downregulation of lncRNA MEG3 and miR-770-5p inhibit cell migration and proliferation in Hirschsprung’s disease

Modulation of the Nur77-Bcl-2 apoptotic pathway by p38α MAPK

Let-7a inhibits migration, invasion and tumor growth by targeting AKT2 in papillary thyroid carcinoma

Application of in vivo imaging techniques to monitor therapeutic efficiency of PLX4720 in an experimental model of microsatellite instable colorectal cancer

Total flavones of abelmoschus manihot enhances angiogenic ability both in vitro and in vivo

Combination treatment with rucaparib (Rubraca) and MDM2 inhibitors, Nutlin-3 and RG7388, has synergistic and dose reduction potential in ovarian cancer

MiR-34a modulates ionizing radiation-induced senescence in lung cancer cells

CANcer-specific Evaluation System (CANES): a high-accuracy platform, for preclinical single/multi-biomarker discovery

The prognostic impacts of TEA domain (TEAD) transcription factor polymorphisms in Chinese hepatocellular carcinoma patients

Von Hippel-Lindau regulates interleukin-32β stability in ovarian cancer cells

NRF2-regulated metabolic gene signature as a prognostic biomarker in non-small cell lung cancer

RNAi-mediated knockdown of Parp1 does not improve the development of female cloned mouse embryos

Low dose of Bisphenol A enhance the susceptibility of thyroid carcinoma stimulated by DHPN and iodine excess in F344 rats

Profiling cancer-associated genetic alterations and molecular classification of cancer in Korean gastric cancer patients

Teriflunomide restores 5-azacytidine sensitivity via activation of pyrimidine salvage in 5-azacytidine-resistant leukemia cells

SF3B1 mutation is a prognostic factor in chronic lymphocytic leukemia: a meta-analysis

Opposing roles of ICAT and Wnt/β-catenin signaling in NSC67657-induced monocytic differentiation

Differential expression of exosomal miRNAs between breast cancer patients with and without recurrence

RGS19 upregulates Nm23-H1/2 metastasis suppressors by transcriptional activation via the cAMP/PKA/CREB pathway

Prognostic value of granulocyte colony-stimulating factor in patients with non-metastatic clear cell renal cell carcinoma

In vitro and in vivo effects of suloctidil on growth and biofilm formation of the opportunistic fungus Candida albicans

Linc-ROR induces epithelial-to-mesenchymal transition in ovarian cancer by increasing Wnt/β-catenin signaling

The diagnostic/prognostic potential and molecular functions of long non-coding RNAs in the exosomes derived from the bile of human cholangiocarcinoma

Characterization of the subcellular localization of Epstein-Barr virus encoded proteins in live cells

Epigenetic silencing of TMEM176A promotes esophageal squamous cell cancer development

Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemoprevention

Longitudinal rotation: a new way to detect the cardiotoxicity of anthracycline-based chemotherapy in breast cancer patients

The prognostic value of osteopontin in limited-stage small cell lung cancer patients and its mechanism

The microRNA expression signature of pancreatic ductal adenocarcinoma by RNA sequencing: anti-tumour functions of the microRNA-216 cluster

Reactive oxygen species dependent phosphorylation of the liver kinase B1/AMP activated protein kinase/ acetyl-CoA carboxylase signaling is critically involved in apoptotic effect of lambertianic acid in hepatocellular carcinoma cells

Physapubescin B inhibits tumorgenesis and circumvents taxol resistance of ovarian cancer cells through STAT3 signaling

Reversible regulation of ORC2 SUMOylation by PIAS4 and SENP2

Long non-coding RNA NEAT1 regulates epithelial membrane protein 2 expression to repress nasopharyngeal carcinoma migration and irradiation-resistance through miR-101-3p as a competing endogenous RNA mechanism

Long non-coding RNA CARLo-5 promotes tumor progression in hepatocellular carcinoma via suppressing miR-200b expression

KIT performed as a driver gene candidate affecting the survival status of patients with stomach adenocarcinoma

Sesquiterpene binding Gly-Leu-Ser/Lys-“co-adaptation pocket” to inhibit lung cancer cell epithelial–mesenchymal transition

Impact of marital status on renal cancer patient survival

TGFβ induced factor homeobox 1 promotes colorectal cancer development through activating Wnt/β-catenin signaling

Apparent diffusion coefficient histogram analysis can evaluate radiation-induced parotid damage and predict late xerostomia degree in nasopharyngeal carcinoma

Alisol B 23-acetate induces autophagic-dependent apoptosis in human colon cancer cells via ROS generation and JNK activation

A new donors’ CYP3A5 and recipients’ CYP3A4 cluster predicting tacrolimus disposition, and new-onset hypertension in Chinese liver transplant patients

The clinical significance of HPIP and the associated prognosis in cervical cancer

Identification of core genes and outcome in gastric cancer using bioinformatics analysis

SSeCKS/AKAP12 scaffolding functions suppress B16F10-induced peritoneal metastasis by attenuating CXCL9/10 secretion by resident fibroblasts

Standardized tumor volume: an independent prognostic factor in advanced nasopharyngeal carcinoma

IL-23R and IL-17A polymorphisms correlate with susceptibility of ankylosing spondylitis in a Southwest Chinese population

Effective antitumor peptide vaccines can induce severe autoimmune pathology

Omeprazole promotes carcinogenesis of fore-stomach in mice with co-stimulation of nitrosamine

Mutational analysis of a Chinese family with oculocutaneous albinism type 2

High-dose atorvastatin reduces the risk of cardiovascular events in patients with percutaneous coronary intervention

A prospective study of serum metabolites and glioma risk

Association between the MVK and MMAB polymorphisms and serum lipid levels

The protective effects of polysaccharide of Atractylodes macrocephala Koidz (PAMK) on the chicken spleen under heat stress via antagonizing apoptosis and restoring the immune function

Acrolein induces mtDNA damages, mitochondrial fission and mitophagy in human lung cells

GMI ablates cancer stemness and cisplatin resistance in oral carcinomas stem cells through IL-6/Stat3 signaling inhibition

Natural killer cell activity for IFN-gamma production as a supportive diagnostic marker for gastric cancer

FOXK1 facilitates cell proliferation through regulating the expression of p21, and promotes metastasis in ovarian cancer

Proapoptotic function of deubiquitinase DUSP31 in Drosophila

The density of mast cells c-Kit⁺ and tryptase⁺ correlates with each other and with angiogenesis in pancreatic cancer patients

A comprehensive study of circulating tumour cells at the moment of prostate cancer diagnosis: biological and clinical implications of EGFR, AR and SNPs

Reverse phase protein array identification of triple-negative breast cancer subtypes and comparison with mRNA molecular subtypes

Cytochalasin B-induced membrane vesicles convey angiogenic activity of parental cells

Overexpression of COL3A1 confers a poor prognosis in human bladder cancer identified by co-expression analysis

Exostosin 1 regulates cancer cell stemness in doxorubicin-resistant breast cancer cells

TFCP2 activates beta-catenin/TCF signaling in the progression of pancreatic cancer

MiR-377 promotes white adipose tissue inflammation and decreases insulin sensitivity in obesity via suppression of sirtuin-1 (SIRT1)

2L-PCA: a two-level principal component analyzer for quantitative drug design and its applications

Dysregulated expression of homeobox family genes may influence survival outcomes of patients with epithelial ovarian cancer: analysis of data from The Cancer Genome Atlas

Validation of the 8th edition of the UICC/AJCC staging system for nasopharyngeal carcinoma treated with intensity-modulated radiotherapy

Calyxin Y sensitizes cisplatin-sensitive and resistant hepatocellular carcinoma cells to cisplatin through apoptotic and autophagic cell death via SCF βTrCP-mediated eEF2K degradation

The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of colorectal cancer

LncSHRG promotes hepatocellular carcinoma progression by activating HES6

The lncRNA HOXA11-AS functions as a competing endogenous RNA to regulate PADI2 expression by sponging miR-125a-5p in liver metastasis of colorectal cancer

Fibronectin in cell adhesion and migration via N-glycosylation

MicroRNA-27b inhibition promotes Nrf2/ARE pathway activation and alleviates intracerebral hemorrhage-induced brain injury

TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway

Non-alcoholic steatohepatitis-related liver tumorigenesis is suppressed in mice lacking hepatic retinoid storage

Adipose-derived mesenchymal stem cells employed exosomes to attenuate AKI-CKD transition through tubular epithelial cell dependent Sox9 activation

Applicability of graded prognostic assessment of lung cancer using molecular markers to lung adenocarcinoma patients with brain metastases

The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertinib in human lung cancer cells

Pharmacokinetics and drug-drug interaction between enalapril, enalaprilat and felodipine extended release (ER) in healthy subjects

MicroRNA-542-3p inhibits oral squamous cell carcinoma progression by inhibiting ILK/TGF-β1/Smad2/3 signaling

Unanticipated prognosis of differential thyroid cancer patients with T0 stage: analysis of the SEER database 2004-2013

Clinical efficacy of endostar combined with chemotherapy in the treatment of peritoneal carcinomatosis in gastric cancer: results from a retrospective study

Epigenetic regulation of interleukin-8 expression by class I HDAC and CBP in ovarian cancer cells

Interaction among CYP2C8, GPIIIa and P2Y12 variants increase susceptibility to ischemic stroke in Chinese population

MicroRNA-466 with tumor markers for cervical cancer screening

Histone deacetylase inhibitor thailandepsin-A activates Notch signaling and suppresses neuroendocrine cancer cell growth in vivo

Prognostic and predictive value of metastatic lymph node ratio in stage III gastric cancer after D2 nodal dissection

Toll-like receptor 3 pathway restricts Marek’s disease virus infection

Different effection of p.1125Val>Ala and rs11954856 in APC on Wnt signaling pathway

Prognostic and predictive value of serum carcinoembryonic antigen levels in advanced non-small cell lung cancer patients with epidermal growth factor receptor sensitive mutations and receiving tyrosine kinase inhibitors

Prognostic role of pretreatment platelet to lymphocyte ratio in urologic cancer

Differentiation between high- and low-grade urothelial carcinomas using contrast enhanced ultrasound

MiR-196a2 and lung cancer in Chinese non-smoking females: a genetic association study and expression analysis

A GLO10 score for the prediction of prognosis in high grade gliomas

Survival outcomes based on systemic agent used concurrently with radiation in human-papillomavirus associated oropharyngeal cancer

Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity

Detection of active proteasome structures in brain extracts: proteasome features of August rat brain with violations in monoamine metabolism

Evidence for the association of chromatin and microRNA regulation in the human genome

Transcriptional downregulation of microRNA-19a by ROS production and NF-κB deactivation governs resistance to oxidative stress-initiated apoptosis

Comprehensive immune transcriptomic analysis in bladder cancer reveals subtype specific immune gene expression patterns of prognostic relevance

Tumor-infiltrating B cells producing antitumor active immunoglobulins in resected HCC prolong patient survival

Aberrant expression of OATP1B3 in colorectal cancer liver metastases and its clinical implication on gadoxetic acid-enhanced MRI

NOGO-B promotes EMT in lung fibrosis via MMP14 mediates free TGF-beta1 formation

Geraniol alleviates LPS-induced acute lung injury in mice via inhibiting inflammation and apoptosis

Role of the CYP3A4-mediated 11,12-epoxyeicosatrienoic acid pathway in the development of tamoxifen-resistant breast cancer

An integrated multigene expression panel to predict long-term survival after curative hepatectomy in patients with hepatocellular carcinoma

MicroRNA-141-3p promotes glioma cell growth and temozolomide resistance by directly targeting p53

Differential diagnosis of hemangiomas from spinal osteolytic metastases using 3.0 T MRI: comparison of T1-weighted imaging, chemical-shift imaging, diffusion-weighted and contrast-enhanced imaging

Identification of candidate genes related to pancreatic cancer based on analysis of gene co-expression and protein-protein interaction network

Imatinib dose escalation versus sunitinib as a second-line treatment against advanced gastrointestinal stromal tumors: A nationwide population-based cohort study

Nomograms incorporated serum direct bilirubin level for predicting prognosis in stages II and III colorectal cancer after radical resection

Surgical resection for hepatic metastasis from gastric cancer: a multi-institution study

The prognostic significance of preoperative left ventricular diastolic dysfunction and left atrial enlargement on acute coronary syndrome in kidney transplantation

RAS testing and cetuximab treatment for metastatic colorectal cancer: a cost-effectiveness analysis in a setting with limited health resources

Combined efficacy of C-reactive protein and red blood cell distribution width in prognosis of patients with culture-negative infective endocarditis

Phase I study of nivolumab combined with IFN-β for patients with advanced melanoma

Dual time-point ¹⁸F-FDG PET/CT imaging with multiple metabolic parameters in the differential diagnosis of malignancy-suspected bone/joint lesions

Negative lymph node count is a significant prognostic factor in patient with stage IV gastric cancer after palliative gastrectomy

State-of-the-art considerations in small cell lung cancer brain metastases

Next-generation sequencing in chronic lymphocytic leukemia: recent findings and new horizons

Immunomodulatory and antitumor effects of type I interferons and their application in cancer therapy

BET inhibitors as novel therapeutic agents in breast cancer

miR-708-5p: a microRNA with emerging roles in cancer

Role of PLZF as a tumor suppressor in prostate cancer

LncRNAs: key players and novel insights into diabetes mellitus

Mitochondrial genome variation and prostate cancer: a review of the mutational landscape and application to clinical management

The resistance mechanisms and treatment strategies for EGFR-mutant advanced non-small-cell lung cancer