DOCK2: A novel FLT3/ITD leukemia drug target

Sleeping through the storm: Preventing myelosuppression with quizartinib

VAV2: a novel prognostic marker and a druggable target for adrenocortical carcinoma

Growth of malignant extracranial tumors alters microRNAome in the prefrontal cortex of TumorGraft mice

Osteoblast-oriented differentiation of BMSCs by co-culturing with composite scaffolds constructed using silicon-substituted calcium phosphate, autogenous fine particulate bone powder and alginate in vitro

High glucose promotes vascular smooth muscle cell proliferation by upregulating proto-oncogene serine/threonine-protein kinase Pim-1 expression

Valproate hampers podocyte acquisition of immune phenotypes via intercepting the GSK3β facilitated NFkB activation

Next generation sequencing identified novel heterozygous nonsense mutation in CNGB1 gene associated with retinitis pigmentosa in a Chinese patient

High-affinity human PD-L1 variants attenuate the suppression of T cell activation

SH003 suppresses breast cancer growth by accumulating p62 in autolysosomes

Mechanism study of isoflavones as an anti-retinoblastoma progression agent

ADAMTS16 mutations sensitize ovarian cancer cells to platinum-based chemotherapy

Targeted interference of SIN3A-TGIF1 function by SID decoy treatment inhibits Wnt signaling and invasion in triple negative breast cancer cells

The tumor suppressor RASSF1A induces the YAP1 target gene ANKRD1 that is epigenetically inactivated in human cancers and inhibits tumor growth

Overexpression of SYF2 promotes cell proliferation and correlates with poor prognosis in human breast cancer

The role of adrenomedullin in the pathogenesis of gastric cancer

Angiotensin-(1-7) counteracts the transforming effects triggered by angiotensin II in breast cancer cells

Anti-cancer effects of dopamine in human glioma: involvement of mitochondrial apoptotic and anti-inflammatory pathways

Novel galeterone analogs act independently of AR and AR-V7 for the activation of the unfolded protein response and induction of apoptosis in the CWR22Rv1 prostate cancer cell model

MicroRNA deregulation in nonalcoholic steatohepatitis-associated liver carcinogenesis

Plasma microRNA alterations between EGFR-activating mutational NSCLC patients with and without primary resistance to TKI

Lack of adiponectin and adiponectin receptor 1 contributes to benign prostatic hyperplasia

Combined Ki67 and ERCC1 for prognosis in non-keratinizing nasopharyngeal carcinoma underwent chemoradiotherapy

Traditional Chinese medicine Danggui Buxue Tang inhibits colorectal cancer growth through induction of autophagic cell death

Plasma N-acetylputrescine, cadaverine and 1,3-diaminopropane: potential biomarkers of lung cancer used to evaluate the efficacy of anticancer drugs

SLC3A2, antigen of mAb 3G9, promotes migration and invasion by upregulating of mucins in gastric cancer

GSK-3β phosphorylation-dependent degradation of ZNF281 by β-TrCP2 suppresses colorectal cancer progression

Differential expression profiles of long non-coding RNAs as potential biomarkers for the early diagnosis of acute myocardial infarction

Toll-like receptor 5 gene polymorphism is associated with breast cancer susceptibility

Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells

Urokinase-type plasminogen activator receptor inhibits apoptosis in triple-negative breast cancer through miR-17/20a suppression of death receptors 4 and 5

Shikonin reduces tamoxifen resistance through long non-coding RNA uc.57

Anti-angiogenic drugs: direct anti-cancer agents with mitochondrial mechanisms of action

Knockdown of long non-coding RNA Taurine Up-Regulated 1 inhibited doxorubicin resistance of bladder urothelial carcinoma via Wnt/β-catenin pathway

Pharmacometabolomics identifies dodecanamide and leukotriene B4 dimethylamide as a predictor of chemosensitivity for patients with acute myeloid leukemia treated with cytarabine and anthracycline

Bioluminescence imaging of a tumor-selective, thymidine kinase-defective vaccinia virus Guang9 strain after intratumoral or intraperitoneal administration in mice

Constitutive activated STAT3 is an essential regulator and therapeutic target in esophageal squamous cell carcinoma

Histone deacetylase 6 inhibition counteracts the epithelial–mesenchymal transition of peritoneal mesothelial cells and prevents peritoneal fibrosis

BCRP expression in schwannoma, plexiform neurofibroma and MPNST

A complex microsatellite at chromosome 7q33 as a new prognostic marker of colorectal cancer

Lung cancer mortality clusters in Shandong Province, China: how do they change over 40 years?

Genetic variants in the inflammation pathway as predictors of recurrence and progression in non-muscle invasive bladder cancer treated with Bacillus Calmette–Guérin

Hyperoside alleviates adriamycin-induced podocyte injury via inhibiting mitochondrial fission

Long noncoding RNA NNT-AS1 promotes hepatocellular carcinoma progression and metastasis through miR-363/CDK6 axis

⁶⁴Cu-ATSM internal radiotherapy to treat tumors with bevacizumab-induced vascular decrease and hypoxia in human colon carcinoma xenografts

Splenectomy is associated with an aggressive tumor growth pattern and altered host immunity in an orthotopic syngeneic murine pancreatic cancer model

Neutrophil/lymphocyte ratio is a more sensitive systemic inflammatory response biomarker than platelet/lymphocyte ratio in the prognosis evaluation of unresectable pancreatic cancer

Notochordal-cell derived extracellular vesicles exert regenerative effects on canine and human nucleus pulposus cells

Association of fibroblast growth factor receptor 1 gene amplification with poor survival in patients with esophageal squamous cell carcinoma

MicroRNA-216a inhibits the metastasis of gastric cancer cells by targeting JAK2/STAT3-mediated EMT process

Association of circulating branched-chain amino acids with cardiometabolic traits differs between adults and the oldest-old

Cost-effectiveness analysis of fecal microbiota transplantation for inflammatory bowel disease

Functional expression of Tim-3 on blasts and clinical impact of its ligand galectin-9 in myelodysplastic syndromes

PARP-1 promotes tumor recurrence after warm ischemic liver graft transplantation via neutrophil recruitment and polarization

Forensic efficiency and genetic variation of 30 InDels in Vietnamese and Nigerian populations

Saikosaponin A inhibits IL-1β-induced inflammatory mediators in human osteoarthritis chondrocytes by activating LXRα

Proteome-based identification of apolipoprotein A-IV as an early diagnostic biomarker in liver fibrosis

SIRT1 promotes tumor-like invasion of fibroblast-like synoviocytes in rheumatoid arthritis via targeting TIMP1

Identification of a gene signature associated with radiotherapy and prognosis in gliomas

Sphingosine kinase 1 mediates diabetic renal fibrosis via NF-κB signaling pathway: involvement of CK2α

Combinatorial effects of an epigenetic inhibitor and ionizing radiation contribute to targeted elimination of pancreatic cancer stem cell

ndmaSNF: cancer subtype discovery based on integrative framework assisted by network diffusion model

Prognostic role of myoferlin expression in patients with clear cell renal cell carcinoma

Marital status and survival in epithelial ovarian cancer patients: a SEER-based study

ACAT-1 gene polymorphism is associated with increased susceptibility to coronary artery disease in Chinese Han population: a case-control study

Association between IL4, IL6 gene polymorphism and lumbar disc degeneration in Chinese population

hYSK1 promotes cancer cell proliferation and migration through negative regulation of p16^INK4a under hypoxic conditions

The heterogeneous CTV-PTV margins should be given for different parts of tumors during tomotherapy

Can polysaccharide K improve therapeutic efficacy and safety in gastrointestinal cancer? a systematic review and network meta-analysis

Risk factors associated with fatality of severe fever with thrombocytopenia syndrome: a meta-analysis

MicroRNA-181 as a prognostic biomarker for survival in acute myeloid leukemia: a meta-analysis

The diagnostic and prognostic value of CHFR hypermethylation in colorectal cancer, a meta-analysis and literature review

Meta-analysis of the clinical value of abnormally expressed long non-coding RNAs for pancreatic cancer

Homeobox protein CDX2 as a prognostic biomarker in solid malignancies: a meta-analysis

Benign and malignant breast lesions identification through the values derived from shear wave elastography: evidence for the meta-analysis

The role of endobronchial ultrasound elastography in the diagnosis of mediastinal and hilar lymph nodes

Time to local recurrence as a predictor of survival in unrecetable gastric cancer patients after radical gastrectomy

The impacts of surgery of the primary cancer and radiotherapy on the survival of patients with metastatic rectal cancer

Impact of preoperative diagnostic TURBT on progression-free survival in patients with pathological high-grade, stage T3/T4 bladder urothelial carcinoma

Characteristics, survival, and risk factors of Chinese young lung cancer patients: the experience from two institutions

Lymph node ratio, but not the total number of examined lymph nodes or lymph node metastasis, is a predictor of overall survival for pancreatic neuroendocrine neoplasms after surgical resection

A phase I trial of NK-92 cells for refractory hematological malignancies relapsing after autologous hematopoietic cell transplantation shows safety and evidence of efficacy

Reassessment of different criteria for diagnosing post-hepatectomy liver failure: a single-center study of 1683 hepatectomy

Sleep in lonely heroin-dependent patients receiving methadone maintenance treatment: longer sleep latency, shorter sleep duration, lower sleep efficiency, and poorer sleep quality

Silibinin: an old drug for hematological disorders

Acetylation and deacetylation in cancer stem-like cells

Management of intracranial melanomas in the era of precision medicine

Predictors of hematoma expansion predictors after intracerebral hemorrhage

Aliskiren therapy in hypertension and cardiovascular disease: a systematic review and a meta-analysis

Calcium influx and sperm-evoked calcium responses during oocyte maturation and egg activation

Hitting the nail on the head: combining oncolytic adenovirus-mediated virotherapy and immunomodulation for the treatment of glioma