What is changing in the adjuvant treatment of melanoma?

Elongation vs stalling: place your BET

Capecitabine for primary breast cancer

Biomarkers in colorectal cancer screening

Cymbopogon citratus and Camellia sinensis extracts selectively induce apoptosis in cancer cells and reduce growth of lymphoma xenografts in vivo

Apatinib alone or combined with radiotherapy in metastatic prostate cancer: Results from a pilot, multicenter study

MiR-19 regulates the proliferation and invasion of glioma by RUNX3 via β-catenin/Tcf-4 signaling

Altered GNAS imprinting due to folic acid deficiency contributes to poor embryo development and may lead to neural tube defects

Survival prediction of kidney renal papillary cell carcinoma by comprehensive LncRNA characterization

Yonsei criteria: a clinical reflection of stage I left-sided pancreatic cancer

EYA2 promotes lung cancer cell proliferation by downregulating the expression of PTEN

A novel messenger RNA signature as a prognostic biomarker for predicting relapse in pancreatic ductal adenocarcinoma

A functional polymorphism of SSBP1 gene predicts prognosis and response to chemotherapy in resected gastric cancer patients

Role and regulation of Yap in Kras^G12D-induced lung cancer

Chitosan composite scaffold combined with bone marrow-derived mesenchymal stem cells for bone regeneration: in vitro and in vivo evaluation

The novel ATM inhibitor (AZ31) enhances antitumor activity in patient derived xenografts that are resistant to irinotecan monotherapy

Evaluating the bias of circRNA predictions from total RNA-Seq data

Dual SIRT1 expression patterns strongly suggests its bivalent role in human breast cancer

High-resolution microbiome profiling uncovers Fusobacterium nucleatum, Lactobacillus gasseri/johnsonii, and Lactobacillus vaginalis associated to oral and oropharyngeal cancer in saliva from HPV positive and HPV negative patients treated with surgery and chemo-radiation

Selenium suppresses inflammation by inducing microRNA-146a in Staphylococcus aureus-infected mouse mastitis model

Increased efficacy of metformin corresponds to differential metabolic effects in the ovarian tumors from obese versus lean mice

Analyzing the influence of kinase inhibitors on DNA repair by differential proteomics of chromatin-interacting proteins and nuclear phospho-proteins

C3G promotes a selective release of angiogenic factors from activated mouse platelets to regulate angiogenesis and tumor metastasis

CXCR4-expressing Mist1⁺ progenitors in the gastric antrum contribute to gastric cancer development

Prexasertib, a cell cycle checkpoint kinases 1 and 2 inhibitor, increases in vitro toxicity of PARP inhibition by preventing Rad51 foci formation in BRCA wild type high-grade serous ovarian cancer

ABCB1 3435TT and ABCG2 421CC genotypes were significantly associated with longer progression-free survival in Chinese breast cancer patients

The association between elevated fasting plasma glucose levels and carotid intima-media thickness in non-diabetic adults: a population-based cross-sectional study

Systemic bioinformatics analysis of recurrent aphthous stomatitis gene expression profiles

Diagnostic performance of ⁶⁸Gallium-PSMA-11 PET/CT to detect significant prostate cancer and comparison with ¹⁸FEC PET/CT

Integrative molecular network analysis identifies emergent enzalutamide resistance mechanisms in prostate cancer

Identifying the dynamics of actin and tubulin polymerization in iPSCs and in iPSC-derived neurons

Discovery of a highly selective KIT kinase primary V559D mutant inhibitor for gastrointestinal stromal tumors (GISTs)

Identification of potential genetic causal variants for rheumatoid arthritis by whole-exome sequencing

Clinical significance of YAP1 activation in head and neck squamous cell carcinoma

Cepharanthine hydrochloride reverses the mdr1 (P-glycoprotein)-mediated esophageal squamous cell carcinoma cell cisplatin resistance through JNK and p53 signals

RIP140 and LCoR expression in gastrointestinal cancers

Sampling from single-cell observations to predict tumor cell growth in-vitro and in-vivo

Inhibition of polo-like kinase 4 (PLK4): a new therapeutic option for rhabdoid tumors and pediatric medulloblastoma

Alteration of mitochondrial biogenesis promotes disease progression in multiple myeloma

Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer

Molecular characteristics and clinical outcomes of EGFR exon 19 indel subtypes to EGFR TKIs in NSCLC patients

MicroRNA-34a inhibits cells proliferation and invasion by downregulating Notch1 in endometrial cancer

Gene expression profiling and construction of a putative gene regulatory network of bladder cancer tumor-initiating cells

Indomethacin-based stimuli-responsive micelles combined with paclitaxel to overcome multidrug resistance

Febuxostat attenuates ER stress mediated kidney injury in a rat model of hyperuricemic nephropathy

Concurrent brain radiotherapy and EGFR-TKI may improve intracranial metastases control in non-small cell lung cancer and have survival benefit in patients with low DS-GPA score

Temozolomide encapsulated and folic acid decorated chitosan nanoparticles for lung tumor targeting: improving therapeutic efficacy both in vitro and in vivo

Aberrant expression of STYK1 and E-cadherin confer a poor prognosis for pancreatic cancer patients

A multicenter prospective phase II study of first-line modified FOLFIRINOX for unresectable advanced pancreatic cancer

MicroRNA-95 promotes myogenic differentiation by down-regulation of aminoacyl-tRNA synthase complex-interacting multifunctional protein 2

Assessment of antimicrobial and wound healing effects of Brevinin-2Ta against the bacterium Klebsiella pneumoniae in dermally-wounded rats

Analysis of the mutational landscape of classic Hodgkin lymphoma identifies disease heterogeneity and potential therapeutic targets

Correlation of psychooncological distress- screening and quality of life assessment in neurosurgical patients

A molecular signature of dormancy in CD34⁺CD38^- acute myeloid leukaemia cells

Antitumor activity of resveratrol against human osteosarcoma cells: a key role of Cx43 and Wnt/β-catenin signaling pathway

Integrating gene and lncRNA expression to infer subpathway activity for tumor analyses

Clinicopathological and prognostic significance of SDC1 overexpression in breast cancer

The effects of tumor necrosis factor-α (TNF-α) rs1800629 and rs361525 polymorphisms on sepsis risk

Chaperonin containing TCP-1 subunit 3 is critical for gastric cancer growth

Methylenetetrahydrofolate reductase tagging polymorphisms are associated with risk of esophagogastric junction adenocarcinoma: a case-control study involving 2,740 Chinese Han subjects

A novel orally available Syk/Src/Jak2 inhibitor, SKLB-850, showed potent anti-tumor activities in B cell lymphoma (BCL) models

Hypoxia-inducible factor-1α regulates microglial functions affecting neuronal survival in the acute phase of ischemic stroke in mice

Hyperbaric oxygen protects against myocardial reperfusion injury via the inhibition of inflammation and the modulation of autophagy

YM155 exerts potent cytotoxic activity against quiescent (G₀/G₁) multiple myeloma and bortezomib resistant cells via inhibition of survivin and Mcl-1

Identification of novel diagnostic biomarkers for thyroid carcinoma

Extracting microtentacle dynamics of tumor cells in a non-adherent environment

Mitochondrial ROS activates ERK/autophagy pathway as a protected mechanism against deoxypodophyllotoxin-induced apoptosis

NLRP6 targeting suppresses gastric tumorigenesis via P14^ARF–Mdm2–P53-dependent cellular senescence

Differential gene expression profiles between two subtypes of ischemic stroke with blood stasis syndromes

High expression of angiogenic factor AGGF1 is an independent prognostic factor for hepatocellular carcinoma

Inhibition of tumor necrosis factor signaling attenuates renal immune cell infiltration in experimental membranous nephropathy

PCPA protects against monocrotaline-induced pulmonary arterial remodeling in rats: potential roles of connective tissue growth factor

Reciprocal sensitivity of diffuse large B-cell lymphoma cells to Bcl-2 inhibitors BIRD-2 versus venetoclax

Next-generation sequencing-based microRNA profiling of mice testis subjected to transient heat stress

CRISPR-Cas9 HDR system enhances AQP1 gene expression

6-(Methylsulfonyl) hexyl isothiocyanate as potential chemopreventive agent: molecular and cellular profile in leukaemia cell lines

Up-regulation of lncRNA SNHG1 indicates poor prognosis and promotes cell proliferation and metastasis of colorectal cancer by activation of the Wnt/β-catenin signaling pathway

Identification of antipsychotic drug fluspirilene as a potential anti-glioma stem cell drug

Identification of bladder cancer prognostic biomarkers using an ageing gene-related competitive endogenous RNA network

LncRNA RNCR3 promotes Chop expression by sponging miR-185-5p during MDSC differentiation

High glucose enhances the metastatic potential of tongue squamous cell carcinoma via the PKM2 pathway

Fatty acid binding protein 4 enhances prostate cancer progression by upregulating matrix metalloproteinases and stromal cell cytokine production

First-line dose-dense chemotherapy with docetaxel, cisplatin, folinic acid and 5-fluorouracil (DCF) plus panitumumab in patients with locally advanced or metastatic cancer of the stomach or gastroesophageal junction: final results and biomarker analysis from an Italian oncology group for clinical research (GOIRC) phase II study

Leucine mediates autophagosome-lysosome fusion and improves sperm motility by activating the PI3K/Akt pathway

Can urologists introduce the concept of “oligometastasis” for metastatic bladder cancer after total cystectomy?

Tumoral immune-infiltrate (IF), PD-L1 expression and role of CD8/TIA-1 lymphocytes in localized osteosarcoma patients treated within protocol ISG-OS1

CRISPR/Cas9-mediated reversibly immortalized mouse bone marrow stromal stem cells (BMSCs) retain multipotent features of mesenchymal stem cells (MSCs)

S-adenosyl-methionine (SAM) alters the transcriptome and methylome and specifically blocks growth and invasiveness of liver cancer cells

ICAM-1 regulates macrophage polarization by suppressing MCP-1 expression via miR-124 upregulation

A plasma miRNA signature for lung cancer early detection

The inhibition of cordycepin on cancer stemness in TGF-beta induced chemo-resistant ovarian cancer cell

IGF-1 induces the epithelial-mesenchymal transition via Stat5 in hepatocellular carcinoma

The impact of antibiotic usage on the efficacy of chemoimmunotherapy is contingent on the source of tumor-reactive T cells

Anti-neoplastic drugs increase caveolin-1-dependent migration, invasion and metastasis of cancer cells

Somatic mutation dynamics in MDS patients treated with azacitidine indicate clonal selection in patients-responders

Long-term effects of sitagliptin in patients with type 2 diabetes mellitus and hypertension: results from the PROLOGUE study

A maternal high-fat diet during pregnancy and lactation, in addition to a postnatal high-fat diet, leads to metabolic syndrome with spatial learning and memory deficits: beneficial effects of resveratrol

A comparison of ARMS-Plus and droplet digital PCR for detecting EGFR activating mutations in plasma

Effect of gene-lifestyle interaction on gestational diabetes risk

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

Curcumin attenuates myocardial ischemia–reperfusion injury

Effect of dihydropyrimidine dehydrogenase single nucleotide polymorphisms on prognosis of breast cancer patients with chemotherapy

Prognostic role of platelet to lymphocyte ratio in esophageal cancer: A meta-analysis

T follicular helper cells: a potential therapeutic target in follicular lymphoma

The regulation of pre-metastatic niche formation by neutrophils

Apelin/APJ system: A key therapeutic target for liver disease

MEF2 signaling and human diseases