Oncotarget

May 22, 2018

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About The Cover

The cover for issue 39 of Oncotarget features Figure 3, "The Integrated Behavior Change model linking perceived autonomy support, autonomous motivation, attitudes, subjective norms, perceived behavioral control, intention and planning on Physical Activity behavior," by Galli, et al.

Table of Contents

Editorial: Autophagy and Cell Death

Autophagy inhibition improves anti-cancer drugs via FOXO3a activation

Autophagy inhibition improves anti-cancer drugs via FOXO3a activation

https://doi.org/10.18632/oncotarget.25366

Brent E. Fitzwalter,  and Andrew Thorburn
25384-25385
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Priority Research Papers

Melanoma-associated mutants within the serine-rich domain of PAK5 direct kinase activity to mitogenic pathways

Melanoma-associated mutants within the serine-rich domain of PAK5 direct kinase activity to mitogenic pathways

https://doi.org/10.18632/oncotarget.25356

Kyle M. LaPak, Dennis C. Vroom, Ayush A. Garg, Xiangnan Guan, John L. Hays, Jonathan W. Song,  and Christin E. Burd
25386-25401
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Gerotarget/Focus on Aging

Active lifestyles in older adults: an integrated predictive model of physical activity and exercise

Active lifestyles in older adults: an integrated predictive model of physical activity and exercise

https://doi.org/10.18632/oncotarget.25352

Federica Galli, Andrea Chirico, Luca Mallia, Laura Girelli, Michelino De Laurentiis, Fabio Lucidi, Antonio Giordano,  and Gerardo Botti
25402-25413
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Research Papers

miR-513a-5p regulates radiosensitivity of osteosarcoma by targeting human apurinic/apyrimidinic endonuclease

miR-513a-5p regulates radiosensitivity of osteosarcoma by targeting human apurinic/apyrimidinic endonuclease

https://doi.org/10.18632/oncotarget.11003

Nan Dai, Yi Qing, Yanping Cun, Zhaoyang Zhong, Chongyi Li, Shiheng Zhang, Jinlu Shan, Xiao Yang, Xiaoyan Dai, Yi Cheng, He Xiao, Chengxiong Xu, Mengxia Li,  and Dong Wang
25414-25426
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Transcriptional activation of p21Waf1 contributes to suppression of HR by p53 in response to replication arrest induced by camptothecin

Transcriptional activation of p21Waf1 contributes to suppression of HR by p53 in response to replication arrest induced by camptothecin

https://doi.org/10.18632/oncotarget.25172

Larisa Y. Romanova, Frederick Mushinski,  and Alexander L. Kovalchuk
25427-25440
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Engineering of a rough auxotrophic mutant Salmonella Typhimurium for effective delivery

Engineering of a rough auxotrophic mutant Salmonella Typhimurium for effective delivery

https://doi.org/10.18632/oncotarget.25192

Jonathan Lalsiamthara, Je Hyoung Kim,  and John Hwa Lee
25441-25457
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

STK3 is a therapeutic target for a subset of acute myeloid leukemias

STK3 is a therapeutic target for a subset of acute myeloid leukemias

https://doi.org/10.18632/oncotarget.25238

Aylin Camgoz, Maciej Paszkowski-Rogacz, Shankha Satpathy, Martin Wermke, Martin V. Hamann, Malte von Bonin, Chunaram Choudhary, Stefan Knapp,  and Frank Buchholz
25458-25473
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Evaluation of appropriate follow-up after curative surgery for patients with colorectal cancer using time to recurrence and survival after recurrence: a retrospective multicenter study

Evaluation of appropriate follow-up after curative surgery for patients with colorectal cancer using time to recurrence and survival after recurrence: a retrospective multicenter study

https://doi.org/10.18632/oncotarget.25312

Tomoki Yamano, Shinichi Yamauchi, Kiyoshi Tsukamoto, Masafumi Noda, Masayoshi Kobayashi, Michiko Hamanaka, Akihito Babaya, Kei Kimura, Chihyon Son, Ayako Imada, Shino Tanaka, Masataka Ikeda, Naohiro Tomita,  and Kenichi Sugihara and Japanese Study Group for Postoperative Follow-up of Colorectal Cancer
25474-25490
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Associations of blood mitochondrial DNA copy number with social-demographics and cancer risk: results from the Mano-A-Mano Mexican American Cohort

Associations of blood mitochondrial DNA copy number with social-demographics and cancer risk: results from the Mano-A-Mano Mexican American Cohort

https://doi.org/10.18632/oncotarget.25321

Hua Zhao, David Chang, Yuanqing Ye, Jie Shen, Wong-Ho Chow,  and Xifeng Wu
25491-25502
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NEDD9 stimulated MMP9 secretion is required for invadopodia formation in oral squamous cell carcinoma

NEDD9 stimulated MMP9 secretion is required for invadopodia formation in oral squamous cell carcinoma

https://doi.org/10.18632/oncotarget.25347

Stéphane Grauzam, Amanda M. Brock, Casey O. Holmes, Jessica A. Tiedeken, Samantha G. Boniface, Bailey N. Pierson, Daniel G. Patterson, Sonya D. Coaxum, David M. Neskey,  and Steven A. Rosenzweig
25503-25516
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Computational development of a molecular-based approach to improve risk stratification of endometrial cancer patients

Computational development of a molecular-based approach to improve risk stratification of endometrial cancer patients

https://doi.org/10.18632/oncotarget.25354

Federica Torricelli, Davide Nicoli, Riccardo Bellazzi, Alessia Ciarrocchi, Enrico Farnetti, Valentina Mastrofilippo, Raffaella Zamponi, Giovanni Battista La Sala, Bruno Casali,  and Vincenzo Dario Mandato
25517-25528
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Selinexor synergizes with dexamethasone to repress mTORC1 signaling and induce multiple myeloma cell death

Selinexor synergizes with dexamethasone to repress mTORC1 signaling and induce multiple myeloma cell death

https://doi.org/10.18632/oncotarget.25368

Christian Argueta, Trinayan Kashyap, Boris Klebanov, Thaddeus J. Unger, Cathy Guo, Susie Harrington, Erkan Baloglu, Margaret Lee, William Senapedis, Sharon Shacham,  and Yosef Landesman
25529-25544
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Bcl-2 inhibition sensitizes triple-negative human breast cancer cells to doxorubicin

Bcl-2 inhibition sensitizes triple-negative human breast cancer cells to doxorubicin

https://doi.org/10.18632/oncotarget.25370

Touko Inao, Yuichi Iida, Tamami Moritani, Tamio Okimoto, Ryosuke Tanino, Hitoshi Kotani,  and Mamoru Harada
25545-25556
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Genome wide DNA differential methylation regions in colorectal cancer patients in relation to blood related family members, obese and non-obese controls – a preliminary report

Genome wide DNA differential methylation regions in colorectal cancer patients in relation to blood related family members, obese and non-obese controls – a preliminary report

https://doi.org/10.18632/oncotarget.25374

S. Pamela K. Shiao, Haiyan Xiao, Lixin Dong, Xiaoling Wang, Kebin Liu, Jinxiong She,  and Huidong Shi
25557-25571
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Diminished gallbladder filling, increased fecal bile acids, and promotion of colon epithelial cell proliferation and neoplasia in fibroblast growth factor 15-deficient mice

Diminished gallbladder filling, increased fecal bile acids, and promotion of colon epithelial cell proliferation and neoplasia in fibroblast growth factor 15-deficient mice

https://doi.org/10.18632/oncotarget.25385

Kunrong Cheng, Melissa Metry, Jessica Felton, Aaron C. Shang, Cinthia B. Drachenberg, Su Xu, Min Zhan, Justin Schumacher, Grace L. Guo, James E. Polli,  and Jean-Pierre Raufman
25572-25585
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Concurrent, but not sequential, PD-1 blockade with a DNA vaccine elicits anti-tumor responses in patients with metastatic, castration-resistant prostate cancer

Concurrent, but not sequential, PD-1 blockade with a DNA vaccine elicits anti-tumor responses in patients with metastatic, castration-resistant prostate cancer

https://doi.org/10.18632/oncotarget.25387

Douglas G. McNeel, Jens C. Eickhoff, Ellen Wargowski, Christopher Zahm, Mary Jane Staab, Jane Straus,  and Glenn Liu
25586-25596
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From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo

From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.25390

Susann Albert, Claudia Arndt, Stefanie Koristka, Nicole Berndt, Ralf Bergmann, Anja Feldmann, Marc Schmitz, Jens Pietzsch, Jörg Steinbach,  and Michael Bachmann
25597-25616
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Baseline splenic volume as a surrogate marker of FOLFIRINOX efficacy in advanced pancreatic carcinoma

Baseline splenic volume as a surrogate marker of FOLFIRINOX efficacy in advanced pancreatic carcinoma

https://doi.org/10.18632/oncotarget.25424

Anne Aarnink, Corentin Richard, Caroline Truntzer, Julie Vincent, Leila Bengrine, Angélique Vienot, Christophe Borg,  and Francois Ghiringhelli
25617-25629
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Combined HAT/EZH2 modulation leads to cancer-selective cell death

Combined HAT/EZH2 modulation leads to cancer-selective cell death

https://doi.org/10.18632/oncotarget.25428

Francesca Petraglia, Abhishek A. Singh, Vincenzo Carafa, Angela Nebbioso, Mariarosaria Conte, Lucia Scisciola, Sergio Valente, Alfonso Baldi, Amit Mandoli, Valeria Belsito Petrizzi, Concetta Ingenito, Sandro De Falco, Valeria Cicatiello, Ivana Apicella, Eva M. Janssen-Megens, Bowon Kim, Guoqiang Yi, Colin Logie, Simon Heath, Menotti Ruvo, Albertus T.J. Wierenga, Paul Flicek, Marie Laure Yaspo, Veronique Della Valle, Olivier Bernard, Stefano Tomassi, Ettore Novellino, Alessandra Feoli, Gianluca Sbardella, Ivo Gut, Edo Vellenga, Hendrik G. Stunnenberg, Antonello Mai, Joost H.A. Martens,  and Lucia Altucci
25630-25646
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia

Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia

https://doi.org/10.18632/oncotarget.25429

Abhishek A. Singh, Francesca Petraglia, Angela Nebbioso, Guoqiang Yi, Mariarosaria Conte, Sergio Valente, Amit Mandoli, Lucia Scisciola, Rik Lindeboom, Hinri Kerstens, Eva M. Janssen-Megens, Farzin Pourfarzad, Ehsan Habibi, Kim Berentsen, Bowon Kim, Colin Logie, Simon Heath, Albertus T.J. Wierenga, Laura Clarke, Paul Flicek, Joop H. Jansen, Taco Kuijpers, Marie Laure Yaspo, Veronique Della Valle, Olivier Bernard, Ivo Gut, Edo Vellenga, Hendrik G. Stunnenberg, Antonello Mai, Lucia Altucci,  and Joost H.A. Martens
25647-25660
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins

Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins

https://doi.org/10.18632/oncotarget.25432

Daniela Heilos, Clemens Röhrl, Christine Pirker, Bernhard Englinger, Dina Baier, Thomas Mohr, Michaela Schwaiger, Shahid Muhammad Iqbal, Sushilla van Schoonhoven, Kristaps Klavins, Tanja Eberhart, Ursula Windberger, Judith Taibon, Sonja Sturm, Hermann Stuppner, Gunda Koellensperger, Rita Dornetshuber-Fleiss, Walter Jäger, Rosa Lemmens-Gruber,  and Walter Berger
25661-25680
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Meta-Analysis

Meta-analysis of homocysteine-related factors on the risk of colorectal cancer

Meta-analysis of homocysteine-related factors on the risk of colorectal cancer

https://doi.org/10.18632/oncotarget.25355

S. Pamela K. Shiao, Amanda Lie,  and Chong Ho Yu
25681-25697
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Dietary cholesterol intake and stroke risk: a meta-analysis

Dietary cholesterol intake and stroke risk: a meta-analysis

https://doi.org/10.18632/oncotarget.23933

Pengfei Cheng, Junxi Pan, Jinjun Xia, Fengli Deng, Wen Huang, Shunjie Bai, Xiaofeng Zhu, Weihua Shao, Haiyang Wang,  and Peng Xie
25698-25707
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Clinical Research Papers

Risk factors for hemoglobinuria after ultrasonography-guided percutaneous microwave ablation for large hepatic cavernous hemangiomas

Risk factors for hemoglobinuria after ultrasonography-guided percutaneous microwave ablation for large hepatic cavernous hemangiomas

https://doi.org/10.18632/oncotarget.25379

Fangyi Liu, Xiaoling Yu, Zhigang Cheng, Zhiyu Han, Jianping Dou, Jie Yu,  and Ping Liang
25708-25713
Abstract  |  PDF  |  HTML  |  How to cite

Lean body mass wasting and toxicity in early breast cancer patients receiving anthracyclines

Lean body mass wasting and toxicity in early breast cancer patients receiving anthracyclines

https://doi.org/10.18632/oncotarget.25394

Federica Mazzuca, Concetta Elisa Onesti, Michela Roberto, Marco Di Girolamo, Andrea Botticelli, Paola Begini, Lidia Strigari, Paolo Marchetti,  and Maurizio Muscaritoli
25714-25722
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Thyroid function in the etiology of fatigue in breast cancer

Thyroid function in the etiology of fatigue in breast cancer

https://doi.org/10.18632/oncotarget.25438

Nagi B. Kumar, Angelina Fink, Silvina Levis, Ping Xu, Roy Tamura,  and Jeffrey Krischer
25723-25737
Abstract  |  PDF  |  HTML  |  How to cite

Reviews

Anticancer drugs-related QTc prolongation, torsade de pointes and sudden death: current evidence and future research perspectives

Anticancer drugs-related QTc prolongation, torsade de pointes and sudden death: current evidence and future research perspectives

https://doi.org/10.18632/oncotarget.25008

Jialin Duan, Jingwen Tao, Maocai Zhai, Chengpeng Li, Ning Zhou, Jiagao Lv, Lin Wang, Li Lin,  and Rong Bai
25738-25749
Abstract  |  PDF  |  HTML  |  How to cite

Corrections

Correction: Neuroprotective effects of bajijiasu against cognitive impairment induced by amyloid-β in APP/PS1 mice

Correction: Neuroprotective effects of bajijiasu against cognitive impairment induced by amyloid-β in APP/PS1 mice

https://doi.org/10.18632/oncotarget.22813

Haobin Cai, Yijie Wang, Jiayang He, Tiantian Cai, Jun Wu, Jiansong Fang, Rong Zhang, Zhouke Guo, Li Guan, Qinkai Zhan, Li Lin, Yao Xiao, Huafeng Pan,  and Qi Wang
25750-25750
Correction  |  PDF  |  How to cite


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