Oncotarget

Volume 4, Issue 9

September 2013

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About The Cover

The association of differentially expressed genes with differently methylated loci. See Luo et al.

Table of Contents

Editorial Materials

Radiation lays down covering fire for viral shock troops

Radiation lays down covering fire for viral shock troops

https://doi.org/10.18632/oncotarget.1187

Joan N Kyula, Aadil A Khan, Michelle J Wilkinson, David Mansfield,  and Kevin J Harrington
1329-1330
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Improving apoptotic responses to targeted therapy

Improving apoptotic responses to targeted therapy

https://doi.org/10.18632/oncotarget.1261

Rizwan Haq,  and David E. Fisher
1331
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Kinase Inhibitor Therapy in CML: It’s What’s Inside That Counts

Kinase Inhibitor Therapy in CML: It’s What’s Inside That Counts

https://doi.org/10.18632/oncotarget.1271

Christopher A. Eide, Brian J. Druker,  and Thomas O’Hare
1332-1333
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Druggable Drivers of Lung Cancer

Druggable Drivers of Lung Cancer

https://doi.org/10.18632/oncotarget.1223

Shameem Fawdar, Zoe C. Edwards,  and John Brognard
1334-1335
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Quo vadis, Kras?

Quo vadis, Kras?

https://doi.org/10.18632/oncotarget.1322

Günter Schneider,  and Dieter Saur
1336-1337
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Research Papers

DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity

DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity

https://doi.org/10.18632/oncotarget.1060

Tatiana N Moiseeva, Andrew Bottrill, Gerry Melino,  and Nickolai A Barlev
1338-1348
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Accumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5

Accumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5

https://doi.org/10.18632/oncotarget.1174

Xu Di, Guofeng Zhang, Yaqin Zhang, Kazuyo Takeda, Leslie A. Rivera Rosado,  and Baolin Zhang
1349-1364
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Loss of PDCD4 contributes to enhanced chemoresistance in Glioblastoma Multiforme through de-repression of Bcl-xL translation

Loss of PDCD4 contributes to enhanced chemoresistance in Glioblastoma Multiforme through de-repression of Bcl-xL translation

https://doi.org/10.18632/oncotarget.1154

Urszula Liwak, Lindsay E Jordan, Sally Davidson Von-Holt, Poonam Singh, Jennifer E. L. Hanson, Ian A Lorimer, Federico Roncaroli,  and Martin Holcik
1365-1372
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Crucial Role for Early Growth Response-1 in the Transcriptional Regulation of miR-20b in Breast Cancer

Crucial Role for Early Growth Response-1 in the Transcriptional Regulation of miR-20b in Breast Cancer

https://doi.org/10.18632/oncotarget.1165

Dongping Li, Yaroslav Ilnytskyy, Anna Kovalchuk, Levon M. Khachigian, Roderick T. Bronson, Bo Wang,  and Olga Kovalchuk
1373-1387
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Coordinated Targeting of the EGFR Signaling Axis by MicroRNA-27a*

Coordinated Targeting of the EGFR Signaling Axis by MicroRNA-27a*

https://doi.org/10.18632/oncotarget.1239

Xiaoli Wu, Mihir K. Bhayani, Cristina T. Dodge, Milena S. Nicoloso, Yunyun Chen, Xiaofeng Yan, Makoto Adachi, Ligy Thomas, Chad E. Galer, Tilahun Jiffar, Curtis R. Pickering, Michael E. Kupferman, Jeffrey N. Myers, George A. Calin,  and Stephen Y. Lai
1388-1398
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness

Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness

https://doi.org/10.18632/oncotarget.1202

Helge Siemens, Rene Jackstadt, Markus Kaller,  and Heiko Hermeking
1399-1415
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

A Hidden Role of the Inactivated FANCD2: Upregulating ΔNp63

A Hidden Role of the Inactivated FANCD2: Upregulating ΔNp63

https://doi.org/10.18632/oncotarget.1217

Jayabal Panneerselvam, Anna Pickering, Jun Zhang, Hong Wang, Hui Tian, Junnian Zheng,  and Peiwen Fei
1416-1426
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Mdig de-represses H19 large intergenic non-coding RNA (lincRNA) by down-regulating H3K9me3 and heterochromatin

Mdig de-represses H19 large intergenic non-coding RNA (lincRNA) by down-regulating H3K9me3 and heterochromatin

https://doi.org/10.18632/oncotarget.1155

Bailing Chen, Miaomiao Yu, Qingshan Chang, Yongju Lu, Chitra Thakur, Danjun Ma, Zhengping Yi,  and Fei Chen
1427-1437
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CXXC5 (Retinoid-Inducible Nuclear Factor, RINF) is a Potential Therapeutic Target in High-Risk Human Acute Myeloid Leukemia

CXXC5 (Retinoid-Inducible Nuclear Factor, RINF) is a Potential Therapeutic Target in High-Risk Human Acute Myeloid Leukemia

https://doi.org/10.18632/oncotarget.1195

Andrey Astori, Hanne Kristin Fredly, Thomas Aquinas Aloysius, Lars Bullinger, Véronique Mansat-De Mas, Pierre de la Grange, Francois Delhommeau, Karen Marie Hagen, Christian Récher, Isabelle Dusanter-Fourt, Stian Knappskog, Johan Richard Lillehaug, Frederic Pendino,  and Øystein Bruserud
1438-1448
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasion

Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasion

https://doi.org/10.18632/oncotarget.1201

Eva Rietkötter, Kerstin Menck, Annalen Bleckmann, Katja Farhat, Meike Schaffrinski, Matthias Schulz, Uwe-Karsten Hanisch, Claudia Binder,  and Tobias Pukrop
1449-1460
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer

Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer

https://doi.org/10.18632/oncotarget.1219

Seok-Jun Kim, Jung-Ah Hwang, Jae Y. Ro, Yeon-Su Lee,  and Kyung-Hee Chun
1461-1471
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Isolation and genome-wide expression and methylation characterization of CD31+ cells from normal and malignant human prostate tissue

Isolation and genome-wide expression and methylation characterization of CD31+ cells from normal and malignant human prostate tissue

https://doi.org/10.18632/oncotarget.1269

Wei Luo, Hu Qiang, Dan Wang, Kristin K Deeb, Yingyu Ma, Carl D Morrison, Song Liu, Candace S Johnson,  and Donald L Trump
1472-1483
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin

Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin

https://doi.org/10.18632/oncotarget.1234

Silvia Cufi, Bruna Corominas-Faja, Eugeni Lopez-Bonet, Rosa Bonavia, Sonia Pernas, Isabel Alvarez Lopez, Joan Dorca, Susana Martinez, Norberto Batista Lopez, Severina Dominguez Martinez, Elisabet Cuyas, Joana Visa, Esther Rodriguez-Gallego, Rosa Quirantes-Pine, Antonio Segura-Carretero, Jorge Joven, Begona Martin-Castillo,  and Javier A Menendez
1484-1495
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The AKT Inhibitor MK-2206 is Cytotoxic in Hepatocarcinoma Cells Displaying Hyperphosphorylated AKT-1 and Synergizes with Conventional Chemotherapy

The AKT Inhibitor MK-2206 is Cytotoxic in Hepatocarcinoma Cells Displaying Hyperphosphorylated AKT-1 and Synergizes with Conventional Chemotherapy

https://doi.org/10.18632/oncotarget.1236

Carolina Simioni, Alberto M. Martelli, Alice Cani, Rengul Cetin-Atalay, James A. McCubrey, Silvano Capitani,  and Luca M. Neri
1496-1506
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Selective anticancer agents suppress aging in Drosophila

Selective anticancer agents suppress aging in Drosophila

https://doi.org/10.18632/oncotarget.1272

Anton Danilov, Mikhail Shaposhnikov, Ekaterina Plyusnina, Valeria Kogan, Peter Fedichev,  and Alexey Moskalev
1507-1526
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Targeting glioblastoma with NK cells and mAb against NG2/CSPG4 prolongs animal survival

Targeting glioblastoma with NK cells and mAb against NG2/CSPG4 prolongs animal survival

https://doi.org/10.18632/oncotarget.1291

Aurelie Poli, Jian Wang, Olivia Domingues, Jesús Planagumà, Tao Yan, Kai Ove Skaftnesmo, Cecilie Brekke Rygh, Frits Thorsen, Emmet McCormack, François Hentges, Paal Henning Pedersen, Jacques Zimmer, Per Øyvind Enger,  and Martha Chekenya
1527-1546
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